2nd most abundant mineral
Phosphorous (85% skeleton, 14% soft tissue)
Inorganic phosphate
phosphoric acid (absorbed to greater extent than organic which occur naturally in whole foods)
Fibroglast growth factor 23 (FGF23)
bone derived hormone suppressing phosphate reabsorption and vitamin d hormone synthesis
which carrier transports three sodium ions for each phosphate
sodium-phosphate, Na-1-Pi (cotransporter NaPi2b)
phosphorus food sources
milk, yogurt, cheeses, eggs, chicken, nuts, seeds, legumes
what is phosphorus used in ultra processed food?
emulsification, pH stability, moisture regulation, color (preservative) found as inorganic phosphate
Inorganic phosphate
Most bioavailable, used in a lot for ultra processed food, may be getting too much
Nova classification (Nova I-Nova IV)
Nova I - unprocessed
Nova IV - ultra processed foods
whole food or UPF need enzymes to liberate from food?
whole food
Phytates
from plant - stomach problems - soaking/sprouting leaches out phytates
increased PTH
increases phosphate uptake/resorption
increased FGF
decreased phosphate uptake/resorption
Regulation and homeostasis which organs
parathyroid, bone, kidney
Lower FGF23 secretion
calcitrol syntheisi increases, leading to increased intestinal phorphorus absorption