during collagen synthesis, vitamin c acts as a reducing agent to keep iron in which state?
ferrous (2+) state (reduced)
humans are unable to synthesize vit c because they lack the enzyme l-gulonolactone oxidase
true
which essential amino acid is a precursor that the body can use to synthesize niacin (vit b3)?
tryptophan
the two main active storage forms of riboflavin in our bodies are FMN and?
FAD
most people in the u.s. meet their daily thiamin needs because many grain products are fortified or enriched
true
the 4-d’s (dermatitis, diarrhea, dementia, death) what deficiency disease?
pellagra (niacin)
which food is rich in thiamin?
pork
Deficiency disease for thiamin
beriberi
which vitamin is responsible for the yellow-green flow seen in milk?
riboflavin
riboflavin is sensitive to uv light and can be destroyed if milk is left in the sun
true
vit b5 is primarily known for being a structural component of which essential metabolic molecule?
coenzyme A (CoA)
vit b6 (as plp) is essential for reactions which involve transferring an amino group from an amino acid to a keto acid (carbon skeleton)
transamination
which neurotransmitter is synthesized from acetyl-coa (vit b5) and choline?
acetylcholine
in fatty acid metabolism, what is a primary role of coenzyme a
it activates fatty acids by converting them to fatty acyl-coa
pantothenic acid (vit 5) is highly toxic, and consuming slightly more than the RDA causes severe liver damage.
false
which specific transporter is used for the absorption fo pantothenic acid (b5) in the intestine, a system shared with biotin and lipoic acid?
SMVT
In the transselenation pathway, a plp-dependent lyase helps generate which selenium-containing amino acid that is then incorporated into seloproteins?
selenocysteine (secys)
decarboxylation
a reaction requiring vit b6 to synthesize neurotransmitters like dopamine and GABA
diahrea
the primary side effect of consuming massive doses (10-20g) of pantothenic acid
alcoholism
reduces absorption (b5)
deamination
a reaction requiring vit b6 to remove an amino group so the molecule can be used for energy.
unlike most water-soluble vitamins, vit b6 is stored extensively in the body. where is 75-80% of it stored?
muscle tissue
the recommended daily intake for vit b5 for general adults?
5 mg/day
what is the primary biochemical function of biotin
carboxylation reactions