Infecto > Poliximas > Flashcards

Poliximas Flashcards

(11 cards)

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1
Q

Bactericidas o bacteriostaticos ?

A

Bactericida

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2
Q

Mecanismo de acción

A

Desorganizan la estructura de la membrana e inhiben la activación del liposacarido

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3
Q

Fármacos?

A

Polimixima B

Polimixima E o Colistina

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4
Q

Vía de administración ?

A

Polimixina B: VO y Tópico

Polimixina E o Colistina: EV e IM

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5
Q

Vía de excreción n

A

Hepatica

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6
Q

Cobertura?

A

Bacilos aerobios multirredistentes
Pseudomonas
Acinetobacter
Enterobacteriaceae

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7
Q

Efectos adversos ?

A 
Nefrotoxicidad 
Neurotoxicidad
Neuropatia periférica 
Bloqueo neuromuscular 
Hipersensibilidad
Convulsiones
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8
Q

Embarazo?

A

No

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9
Q

BHE

A

No

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10
Q

Indicaciones ?

A 
Infecciones por bacterias gram negativos resistentes a carbapenemicos
Infección de piel y tejidos blandos 
Otitis 
Infecciones oftalmologicas
NAV
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11
Q

Nota

A

No cubre proteus, providencia ni Serratia

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