1
Q
what is it
A
chronic disorder with progressive destruction of small bile ducts
2
Q
what does it lead to
A
cirrhosis
3
Q
more common in men or women
A
women
4
Q
what are found in most patients
specific to PBC
A
serum anti-mitochondrial antigen M2
5
Q
symptoms (5)
A
- pruritus
- fatigue
- jaundice
- hepatomegaly.
- xanthelasma
6
Q
associated disorders
A
- autoimmune
- keratoconjunctivitis Wicca (dry eyes and mouth)
- renal tubular acidosis
- coeliac disease
- interstitial pneumonitis
7
Q
investigations
A
- mitochondrial antibodies (ELISA)
- ultrasound
- biopsy
8
Q
are hepatic granulomas present
A
yes
9
Q
treatment (3)
A
- ursodeoxycholic acid
- steroids
- liver transplant
10
Q
how is pruritus controlled.
A
- colestyramine
- rifampicin !
11
Q
complications (3)
A
- cirrhosis
- osteoporosis
- osteomalacia
12
Q
what should patients with jaundice be ordered
A
liver transplant
GI
flashcards
Decks in class (50)
# Cards
-
investigations24
-
LFT7
-
physiology406
-
anatomy129
-
acute abdomen - appendicitis23
-
acute liver failure11
-
alcoholic liver disease19
-
alpha1- antitrypsin deficiency8
-
anorectal disorders - haemorrhoids, anal fissure, fistula in ano15
-
ascites8
-
biliary tract tumours15
-
budd-chiari syndrome11
-
cirrhosis22
-
coeliac disease32
-
coeliac disease14
-
crohns33
-
diarrhoea32
-
diverticular disease23
-
gallstones34
-
gastroenteritis85
-
gi bleeding40
-
haemochromatosis16
-
hepatitis59
-
IBS6
-
jaundice35
-
large intestine25
-
large intestine miscellaneous18
-
large intestine tumours48
-
liver77
-
liver biochemistry16
-
liver infections14
-
liver tumours20
-
miscellaneous intestinal diseases22
-
mouth29
-
oesophagus75
-
pancreas41
-
pancreatic cancer42
-
pancreatitis59
-
peritoneum10
-
portal hypertension7
-
primary biliary cholangitis12
-
primary sclerosing cholangitis9
-
small inestine103
-
small intestine resection23
-
small intestine tumours31
-
stomach and duodenum - peptic ulcer133
-
tropical sprue15
-
ulcerative colitis34
-
wilsons12
-
functional disorders0
