Principles 1

Question 1

How do you get a xenobiotic to the brain?

Answer 1

absorption
distribution
metabolism
elimination

Question 2

what are some advantages and disadvantages of oral pharmokinetics

Answer 2

potential large duration of action
compliance is easier
potential liver damage

Question 3

what are some advantages and disadvantages of intervenus pharmokinetics

Answer 3

immediate bioavailability
some risks
no first past effect
better to control plasma concentration

Question 4

what are some advantages and disadvantages of transdermal pharmokinetics

Answer 4

slow steady absorption
control location of action
can be manipulated by the temperature