Protein Structure

Question 1

Define primary structure

Answer 1

number and sequence of amino acids

Question 2

What are the bonds of the primary structure?

Answer 2

peptide (covalent)

Question 3

Name the types of secondary structures

Answer 3

• Alpha helix
• Beta pleated sheets
• Beta bends
• Loop regions

Question 4

What are the bonds of an alpha helix?

Answer 4

H+ bonds and vander waals forces

Question 5

What are the bonds of the Beta pleated sheets?

Answer 5

H bonds

Question 6

Define tertiary structure

Answer 6

spatial arrangement between secondary and “supersecondary” elements

Question 7

What are the types of bonds in the tertiary structure?

Answer 7

disulfide, H bonds, salt bridges, hydrophobic interactions

Question 8

What types of proteins have tertiary structures?

Answer 8

enzymes & hemoglobin

Question 9

Define quaternary structure

Answer 9

assembly of 2 or more separate peptide chains

Question 10

Name a dimeric protein

Answer 10

Cu-Zn superoxide dismutase

Question 11

Name a trimeric protein

Answer 11

tropocollagen (collagen)

Question 12

What amino acids are in the trimeric protein?

Answer 12

• glycine
• hydroxylysine
• hydroxyproline

Question 13

What vitamin is needed to synthesize the amino acids in the trimeric protein?

Answer 13

vitamin C

Question 14

Name a tetrameric protein

Answer 14

hemoglobin

Question 15

What mineral is needed for this tetrameric protein?

Answer 15

iron

Question 16

What amino acids are in loop regions?

Answer 16

proline or glycine