Protein from greek word …
Proteis meaning “first rank of importance”
Proteins are synthesized in the …
Liver by the hepatocytes
Proteins are synthesized in the liver except
Immunoglobulins
Proteins provide how many percent of total daily body energy requirements
12-20%
Proteins are how many percent of the cell’s dry weight
50-70%
It is the linear sequence of the amino acid
Primary structure
It determines the identity of protein, and molecular structure …
Primary structure
It involves the winding of the polypeptide chain
Secondary structure
It is the actual 3-dimensional configuration; the folding pattern of the protein
Tertiary structure
Responsible for many of the physical and chemical properties of the proteins
Tertiary structure
It is the association of 2 or more polypeptide chains to form a functional protein molecule
Quaternary structure
They contain peptide chains which on hydrolysis yield only amino acids
Simple proteins
Composed of protein and a non-protein moiety
Conjugated proteins
It is when a protein catabolism exceeds anabolism
Negative nitrogen balance
It is when a protein anabolism exceeds catabolism
Positive nitrogen balance
It migrates ahead of albumin
Prealbumin (transthyretin)
Prealbumin transports …
T4 and Retinol (Vitamin A)
It is the protein with the highest concentration in plasma
Albumin
A general transport protein
Albumin
Albumin is a type of what reactant phase
Negative acute phase reactant
The reference value of Albumin
3.5-5.0 g/dL
It is a group of proteins consists of a1, a2, B, and Y fractions
Globulins
It is a major inhibitor of protease activity - prevents self-destruction of tissue
a1-antitrypsin
It is synthesized initially by the fetal yolk sac and then by the fetal parenchymal cells of the liver
a1-fetoprotein
