Pseudomonas spp

Question 1

Major characteristic of Pseudomonas

Answer 1

production of extracellular slime layer; produces blue green pus in infections
highly resistant to number of antimicrobials

Question 2

Major pathogen that causes otitis externa in dogs

Answer 2

Pseudomonas spp.

Question 3

What infection can Pseudomonas spp cause in sheep

Answer 3

Fleece rot

Question 4

Describe fleece rot caused by pseudomonas spp

Answer 4

• key infection, causing discolouration and pigmentation of the fleece
• causes dermatitis after wetting, as the aerobic environment after rain allows Pseudomonas from the skin or soil to proliferate

Question 5

Pseudomonas spp on horses & cows

Answer 5

Pseudomonas can cause abortion and metritis, acting as an opportunistic pathogen

Question 6

Pseudomonas spp in poultry

Answer 6

Can cause septicaemia and dermatitis

Question 7

Otitis externa in dogs Pseudomonas spp

Answer 7

• can be a primary infection or a secondary invader after another infection
• The presence of green pustules suggests Pseudomonas involvement
• Other infections in dogs include cystitis, dermatitis, and prostatitis

Question 8

Mechanisms of intrinsic resistance of Pseudomonas spp

Answer 8

1. Lower permeability of intrinsic resistance
   
   1. prevents many drugs from entering the bacterial cells
2. Multidrug efflux pumps
   
   1. actively pump antimicrobials out of the cell if they do manage to enter
3. Chromosomally produced Beta-lactamases
   
   1. enzymes that neutralise beta-lactam antibiotics (like penicillins and cephalosporins), rendering them ineffective