two categories
gastric
duodenal
Mgx
If h.pylori +ve - eradication therapy
Lifestyle
PPI (omerprazole)
H2 RA
Zollinger-ellison syndrome
Gastrinoma
In head of pancreas or duodenum
release gastrin
Causes stomach to produce more acid
H.pylori
colonises antrum
causes inflammation
Damages gastric mucosa
Forms ulcerations
NSAIDs
Inhibits COX 1
Decreases prostaglandins, which protect
Abrasions to stomach will be unable to heal
Pepsin can cause ulcerations
Smoking
Decreases prostaglandin synthesis
Ix
FBC
LFTs
Amylase
UGI endoscopy
H. pylori testing
Urea breath test
\Bloods - checks for IgG
Stool antigen
Urease