Features of serotonin syndrome
3As
Plummer-vinison syndrome characterised by triad of what:
Plummers DIE
D- dysphagia
I- iron deficiency anaemia
E- eosophageal webs
A 5-year-old boy presents with recurrent episodes of sinusitis. The casualty staff are surprised to find his liver lying in the left upper quadrant of the abdomen
Kartagener’s syndrome
- immotile cilia syndrome
- assocaited with sinus inversus
What is vestibular neuronitis?
–> cause of vertigo
–> develops following viral infection
Features:
1. recurrent vertigo attacks lasting hours or days
2. nausea and vomiting may be present
3. horizontal nystagmus is usually present
4. no hearing loss or tinnitus
Differentiating vestibular neuronitis from posterior circulation stroke
HiNTs exam
Management of vestibular neuronitis:
mydriasis
dilated eye
miosis
smaller pupil
3rd nerve palsy characterised by:
Status epilepticus management
Management
1. ABC
2. BENZOs
–> Prehospital –> PR diazepam or buccal midazolam
–> Hospital IV lorazepam –> repeated once after 5-10 mins
3. Established status
–> leve, phenytoin, sodium valproate
4. No response w/i 45 mins?
–> call the anaesthetist!–> RSI
Mx Bells palsy
51 y/o female
PC: facial flushing + diarrhoea
HPC: 6/12 facial flushing, worse on exertion, associated palpitations. 3/12 diarrhoea.
OE: peripheral oedema, soft mid-diastolic murmur
characteristic of:
CARCINOID SYNDROME
–> secretion of serotonin, kinins and amines leads to flushing
Murmur –> tricuspid stenosis, R heart failure
Investigation for carcinoid syndrome
24 hour collection of urinary 5-HIAA
Management of carcinoid syndrome
What occurs in primary hyperparathyroidism?
Cause –> solitary parathyroid adenoma –> increase release of PTH
Result:
–> high calcium and low phosphate
–> increase bone turnover by OC activation –> more ALP
Presentation: hypercalcaemia symptoms: constipation and mood changes
Describe secondary hyperparathyroidism:
Chronically low serum [Ca2+] –> parathyroid hyperplasia
Increased PTH secretion will not be able to reverse chronically low calcium and high phosphate caused by condition.
PTH –> excessive bone turnover –> high ALP
Presentation: bone pain, tenderness, proximal myopathy and recurrent fractures
Tertiary hyperparathyroidism is caused by:
ongoing hyperplasia of parathyroid glands after correction of long standing renal disorder.
Presentation of tertiary hyperparathyroidism
management of endometrial hyperplasia
Simple w/o atypia –> high dose progestogens with repeat sampling in 2-4 months. maybe IUS.
If Atypia: HYSTERECTOMY w/ bilateral salpingectomy
what sound be suspected in a patient who develops post operative shortness of breath and hypoxaemia
Atelectasis
management of atelectasis
What rules are used to minimise use of X-rays in patients presenting with ankle injuries
OTTAWA ANKLE RULES
Weber classification
A - below syndesmosis (CAM + weight bearing)
B- tibial plafond may extend proximally to involve syndesmosis
C - above syndesmosis (ORIF)
What is Wolff-Parkinson-White syndrome?
Possible ECG features
- short PR
- widened QRS