anaphylaxis adrenaline
dose 1mg/ml or 1:1000
12+ years: 500 mcg
6-12 years: 300 mcg
6 months - 6 years: 150mcg
0-6 months: 100-150mcg
fluid bolus
adults: 0.5-1L
children: 10ml/kg
U classification thyroid
U1 (no FNA C)
normal thyroid
U2 (no FNA C)
isoechoic or slightly hyper echoic
hypoechoic halo
hypoechoic (cystic) nodule with colloid
-(normal thyroid hormone store - dense comet tail)
spongiform/honeycomb
peripheral egg shell
peripheral vascularity
U3 (indeterminate - needs FNA C)
homogeneous hyper echoic
echogenic solid component
mixed vascularity (peripheral and central)
U4 (suspicious - needs FNA C)
solid hypoechoic
incomplete ring calc
lobulated outline
U5 (malignant - needs FNA C)
solid hypoechoic lobular outline
papillary - microcalc
medullary - macro/globular calc
taller than wide
internal vascularity
U2 needs FNA C if it has suspicious clinical features:
Age <20 or > 60 years
firm
fast growing
vocal cord paralysis
regional LNs
previous neck RT
fam hx of thyroid cancer
most sensitive and specific indicator of thyroid malignancy
microcalc
Li Fraumeni syndrome
mutation of the tumour suppressor gene TP53
invasive cancer by age 30
can’t give ionising X-ray in this mutation
sarcomas
gliomas
choroid plexus carcinoma
medulloblastoma
neuroectodermal tumours
leukaemia
breast cancer
adrenal cortical carcinoma
Annual breast MRI from 20 to 70
mammogram is contraindicated
if breast irradiated between 10-20
annual MRI from age 25 or 8 years after first irradiation, whichever is the later
if breast irradiated between 20 and 36
annual MRI from age 30 or 8 years after first irradiation, whichever is the later
perimesencephalic SAH with normal CT angiogram
anterior to pons and midbrain
no further test or imaging needed
perimesencephalic is non aneurysmal
venous bleed related
CT should have been within 3 days
can settle in occipital ventricles
most common salter Harris fracture
type 2
SALTER fracture with the worst prognosis
type 5
how long to hold THERAPEUTIC LMWH before TACE
24 hour hold - therapeutic LMWH - all moderate or high risk interventions
12 hour hold - prophylactic LMWH
moderate risk (arterial intervention, embolisation, TACE, UAE, PAE, dialysis lines, tunnel lines).
high risk (large arterial intervention, aortic stent, tumour ablation, nephrostomy, renal liver biopsy, biliary intervention)
Bosniak
2f - thick and nodular calc
FU 6 months, 12 months, then annually for 5 years
3 - measurable enhancement
4 - solid component
bosniak 3 - measurable enhancement of walls - partial nephrectomy or RFA
LCH
irregular nodules
irregular cysts
normal or large lung volumes
CP angles spared
LAM vs emphysema
emphysema has central dot
LAM causes lymphatic obstruction - chylous effusion
RB-ILD
The nodules are centrilobular
teratoma vs thymoma
teratoma is slow growing and long standing
thymoma appears and causes pleural effusion
thymoma spreads to pleura
obscures left heart border
anterior mediastinal mass
military TB
immunocompromised
random nodules 1-3mm
happens in primary and post primary TB when it spreads haematogeneously
splenomegaly
PJP
perihilar and upper zone ground glass
no lymphadenopathy
castleman
angioimmunoblastic
intensely enhances unlike lymphoma
swyer James
air trapping
hypoplasia
small pulmonary vessels
underdeveloped lung
HP
granulomatous involvement of small airways
air goes in but gets trapped
superior mediastinal mass that fades above the clavicle
retrosternal goitre
posterior mediastinal masses well defined above the clavicle
high attenuation lesions in the brain on non con CT
most likely is melanoma
axillary clips
breast cancer in a woman
melanoma in a man
liver biopsy
large volume ascites is a contraindication (risk of bleed and harder to target)
trans jugular liver biopsy - for non targeted biopsy
need 6 core biopsies
use coaxial needle - minimises bleed risk (only one puncture of the liver capsule)
biopsy edge of lesion (less vascular)
ascites and IHBD is a CI