normal adult small bowel length
400-800 cm (avg 630 cm men and 590 cm women)
how much small bowel remaining to reduce PN dependency with jejunoileocolonic anastomosis?
30 cm
how much small bowel remaining to reduce PN dependency with jejunocolonic anastomosis?
60 cm
how much small bowel remaining to reduce PN dependency with end jejunostomy?
100 cm
*most likely to require permanent PN compared to jejunocolonic anastomosis and jejunoileocolonic anastomosis
terminal ileum is primary site for….
B12 absorption and enterohepatic recirculation of bile
how is bile loss impacted when >100 cm of terminal ileum is resected?
the amount of unrecycled bile loss > maximum rate of hepatic bile synthesis
-causes bile insufficiency, fat malabsorption, steatorrhea
when > ____ cm of terminal ileum is resected, sites of B12 absorption are decreased thus increasing deficiency risk
60 cm
ileal brake
slows GI transit in response to enteric hormones (GLP-1, GLP-2, peptide YY)
how is ileal brake impacted in a partial or complete ileal resection?
mechanism is compromised and contributes to acceleration of GI transit
role of colon in hydration
absorbs water from stool and helps decrease dehydration risk
where is site for bacterial fermentation of fiber and malabsorbed CHOs into SCFAs?
colon
which part of small intestine is responsible for most of nutrient absorption?
jejunum
-macros, mag, calcium, B vitamins (except B12), cholesterol, zinc, FSV, vitamin C
which part of small intestine has most potential for intestinal adaptation?
ileum (then colon), duodenum and jejunum has least adaptation potential
goals for UOP and urine Na in SBS
UOP >1 L/day
Urine Na >20 mEq/L
how can hypomagnesemia lead to hypocalcemia?
impaired PTH release
approaches to decrease PNALD risk in SBS
trophic EN, cyclical PN, use of ILEs with lower soybean oil content, close monitoring of mineral toxicities
nephrolithiasis is a risk in SBS patients with or without a colon in continuity?
with
why is nephrolithiasis a risk in SBS in those with colon in continuity?
-dietary oxalate usually binds to Ca and is excreted via stool
-HOWEVER, in presence of fat malabsorption > fat present in colon > calcium binds to fat > oxalates absorbed in blood
nephrolithiasis nutrition management
low fat, low oxalate, high calcium, proper hydration
why is metabolic bone disease a risk in SBS?
poor calcium and vitamin D absorption and secondary hyperparathyroidism
what are important considerations of fluid components in SBS? why are these important to consider?
osmolality, sodium content, glucose content
*b/c inappropriate fluids will exacerbate fluid losses in SBS
are commercial sports drinks an acceptable ORS in SBS?
no
what type of bowel resection/anastomosis location should have ORS as primary hydration source?
end jejunostomy
pts with <___% of colon may benefit from ORS
50%