SCLC

Question 1

Morphology of SCLC on pathology

Answer 1

small round blue cell tumor

Question 2

SCLC stains

Answer 2

chromogranin
synaptophysin
NCAM
*CD56
TTF1

Question 3

Paraneoplastic syndromes associated with SCLC

Answer 3

Limbic encephalitis
SIADH
LEMS
Cortico-cerebellar degeneration
Cushings

Question 4

Clinical benefit of PCI in SCLC

Answer 4

OS benefit

Question 5

1) Surgically resectable SCLC based on stage 2) surgery type

Answer 5

1) I-IIA 2) Lobectomy

Question 6

Second line for SCLC

Answer 6

• IF relapse >6 months, rechallenge platinum/etoposide
  IF relapse <6 months, lurbinectedin vs. topotecan

Question 7

What is resectable disease in limited stage small cell

Answer 7

no hilar or mediastinal lymph node involvement

Question 8

Suprahilar edema post LS SCLC management

Answer 8

observation (radiation SE)