SIADH

Question 1

What does SIADH stand for?

Answer 1

Syndrome of inappropriate ADH secretion

Question 2

What happens in SIADH?

Answer 2

Too much ADH secretion so too much water is reabsorbed

Question 3

What are serum levels in SIADH?

Answer 3

1. serum Na is LOW
2. Urine osmo HIGH
3. urine Na is HIGH

Question 4

Is SIADH a diagnosis?

Answer 4

not final diagnosis need to find cause

Question 5

What are CNS causes of SIADH?

Answer 5

1. SAH
2. stroke
3. tumour
4. TB

Question 6

What are pulmonary causes of SIADH?

Answer 6

1. pneumonia

2. bronchiectasis

Question 7

What are malignancy causes of SIADH?

Answer 7

small cell lung cancer

Question 8

What are drug causes of SIADH?

Answer 8

1. carbamazepine

2. SSRI

Question 9

What are causes of SIADH?

Answer 9

1. CNS: SAH, stroke, tumour, TB
2. Pulmonary: pneumonia, bronchiectasis
3. Malignancy: small cell lung cancer
4. Drugs: carbamazepine, SSRI
5. . Idiopathic

Question 10

What is the management for mild/moderate for SIADH?

Answer 10

• Treat cause (e.g., surgery for tumour)

* Immediate fluid restriction (for hyponatraemia)

Question 11

What do you do if treatment is innefective in SIADH?

Answer 11

oral demeclocycline (makes collecting ducts less responsive to ADH)/IV vaptans