Sleep Disorders Flashcards

(20 cards)

1
Q

Chronic insomnia diagnosis

A

symptoms at least 3 times per week for at least 3 months

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2
Q

What drugs can worsen insomnia?

A

Acetylcholinesterase inhibitors
Alcohol
Aripiprazole
Atomoxetine
Bupropion
Caffeine
Decongestants
Diuretics
Fluoxetine
Nicotine
INSTIs
Steroids
Stimulants
Varenicline

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3
Q

What sleep agents help falling asleep? Staying asleep? Both?

A

fall asleep: ramelteon, zaleplon
stay asleep: doxepin, suvorexant
both: eszopiclone, zoldipem

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4
Q

Lunesta

A

eszopiclone (C-IV)

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5
Q

Ambien

A

zoldipem (C-IV)

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6
Q

Edluar

A

zoldipem SL tablet

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7
Q

Zoldipem dosing for females, males, and older adults

A

male: 5-10 mg
female: 5 mg
older: 5 mg

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8
Q

Non-BZD hypnotics, MoA

A

eszopiclone, zolpidem, zaleplon
act selectively at BZD receptors to increase GABA

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9
Q

Non-BZD hypnotics safety

A

potential for abuse
Beers criteria

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10
Q

Orexin receptor antagonists

A

daridorexant
lemborexant
suvorexant

all C-IV

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11
Q

Melatonin receptor agonists

A

ramelteon
tasimelteon

not controlled

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12
Q

Which tricyclic antidepressant can be used for insomnia

A

doxepin

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13
Q

Restoril

A

temazepam
C-IV

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14
Q

Which antidepressants can be used for insomnia

A

diphenhydramine
doxylamine

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15
Q

Unisom SleepTabs

A

doxylamine

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16
Q

Antihistamine safety

A

anticholinergic effects (urinary retention, dry mouth, dry eyes/blurry vision, constipation)
avoid use in BPH and glaucoma

17
Q

Treatment for restless leg syndrome

A

dopamine agonists: pramipexole, ropinirole, rotigotine patch
gabapentin

18
Q

Treatment for narcolepsy

A

modafinil, armodafinil
sodium oxybate
pitolisant, solriamfetol
dexmethylphenidate, Adderall, methylphenidates

19
Q

sodium oxybate safety

A

derived from GABA
C-III
REMS only (used illicitly and for sexual assault)

20
Q

Silenor