SPE patterns

Question 1

Which proteins are made by the liver

Answer 1

-Albumin
-Alpha and beta globulins

Question 2

Polyclonal gammopathy

Answer 2

Broad based peak in beta and gamma globulins
Consistent with inflammation

Question 3

Monoclonal gammopathy

Answer 3

Tall narrow peak similar to albumin in gamma globulins
Myeloma, plasmacytoma, lymphoma, CLL

Question 4

Restricted polyclonal gammopathy

Answer 4

Peak superimposed on a wider polyclonal base usually IgG
From infectious agents like Ehrlichia or long standing inflammation