How to remember encapsulated organisms?
Some Killers Have Perfectly Nasty Capsules S. pneumo Klebsiella H flu Pseudomonas Neisseria meningitidis Cryptococcus neoformans
Who gets encapsulated infections?
Asplenic patients
What do fluoroquinolones cover? What is their MOA?
Broad spectrum with both gram positive and gram negative coverage
Cover pseudomonas
Work by inhibiting DNA synthesis the bacterial topoisomerase protein.
What are the anti-psuedomonal penicillins?
Ticeracillin
Piperacillin
Which cephalosporin covers pseudomonas?
Ceftazidime
What does aztreonam cover?
Gram negative rods
Can be used in patients who are penicillin allergic
Why is trimethoprim commonly given with sulfamethoxazole as TMP-SMX?
These agents inhibit folic acid synthesis at different steps, meaning their combination is synergistic