Study guides for exam 2

Question 1

What is the impact of the blood brain barrier and CNS drugs?

Answer 1

a large percentage of drugs are carried bound o plasma proteins and are unable to cross into the brain

Question 2

major adverse effect of SSRI’s

Answer 2

serotonin syndrome

Question 3

most anticholinergic SSRI

Answer 3

paroxetine

Question 4

what is the good levels of lithium in the blood plasma

Answer 4

0.8–1.4 mEq/L

Question 5

Signs of lithium toxicity

Answer 5

Serious CNS effects ranging from coarse hand tremor and vertigo to seizures and coma – severe toxicity can lead to death

Question 6

adverse effects of carbamazepine

Answer 6

leukopenia
anemia
 teratogenesis
 hyposmolalit
 hepatotoxicity
 CNS effects