Sympathomimetics ANS

Question 1

What is a catecholamine And what metabolize it

Answer 1

A Dihydroxyphenylethylamine derivative 
Chatachol-O-methyltransferase

Question 2

Name an alpha Agonist That causes mydriasis

Answer 2

Phenylephrine

Question 3

Which Beta agonists drugs are used for reversing bronchospasm

Answer 3

Albuterol
isoproterenol
Metaproteranol
Terbutaline

Question 4

Which type of receptor agonist decreases salt and water secretion into the intestine

Answer 4

Alpha two

Question 5

What are the effects of alpha-one agonists on vascular system

Answer 5

1. Contract vascular smooth muscle
2. Increase peripheral vascular resistance
3. Venous pressure

Question 6

Name alpha-2 agonist effect on vascular system

Answer 6

Vasoconstriction

Question 7

What are the effects of beta - 2 Agonists on the vascular system

Answer 7

1. Reduce arterial tone in skeletal muscle vascular beds 
2. Reduce Vascular resistance and arterial blood pressure

Question 8

What are the effects of dopamine on the vascular system

Answer 8

Vasodilation in splenic and Renal vascular beds by activating D1 receptors

Question 9

What is the effect of a pure alpha agonist on heart rate

Answer 9

Routinely slows heart rate via baroreceptor reflex

Question 10

What are the effects of pure beta agonist on heart rate

Answer 10

Almost always increases heart rate

Question 11

Which Adrenoceptor has the greatest effect on vascular resistance

Answer 11

Alpha and beta two

Question 12

Which receptor influences pulse pressure

Answer 12

Beta one

Question 13

Which type of Agonist increases renin secretion 

Answer 13

Beta one agonist

Question 14

Which agonist increases insulin secretion

Answer 14

Beta two 

Question 15

What is the drug of choice for immediate treatment of anaphylactic shock

Answer 15

Epinephrine 

Question 16

Which drugs are used in ADHD

Answer 16

1. Methylphenidate
2. Amphetamine
3. methamphetamine

Question 17

Name two alpha agonists used in the eye to reduce conjunctive itching and irritation

Answer 17

Tetrahydrozoline
Phenylephrine 

Question 18

Name two alpha-2 agonist used in glaucoma

Answer 18

Apraclonidine
Brimonidine

Question 19

Name a drug that can be used for AV block

Answer 19

Isoproterenol

Question 20

Name direct acting catecholamines

Answer 20

1. Epinephrine
2. Norepinephrine
3. dopamine
4. isoproterenol
5. Dobutamine

Question 21

Name non-catecholamine alpha selective agonists

Answer 21

Phenylephrine
Methoxamine
Clonidine

Question 22

Name non-catecholamines beta 2 selective agonist

Answer 22

1. Albuterol
2. terbutaline
3. metaproterenol
4. Salmeterol
5. Formoterol
6. Indacaterol
7. Vilanterol
8. Olodaterol

Question 23

Name indirect acting phenylisoproplamines agonists

Answer 23

1. Amphetamine
2. methamphetamine
3. ephedrine

Question 24

What is the effect of adrenaline an anaphylactic shock

Answer 24

1. Cardiac stimulation
2. increased blood pressure
3. increased peripheral resistance
4. decreased mucosal edema
5. decrease release of mediators from mast cells
6. antagonist of histamine

Question 25

What are the therapeutic uses of beta two selective Agonists

Answer 25

1. Bronchial asthma 2. delay premature labour 3. hyperkalaemia

Question 26

Name the drug Whose main action is on the uterus and prevents premature labour

Answer 26

Ritodrine 

Question 27

What are the adverse effects of using beta two agonists 

Answer 27

1. Tremor 2. Tachycardia 3. hyperglycaemia 4. hypokalaemia

Question 28

Name nasal decongestants 

Answer 28

1. Naphazoline 2. Oxymetazoline 3. Xylometazoline 4. Pseudoephedrine 5. Phenylephrine

Question 29

Name selective alpha-2 agonist

Answer 29

1. Clonidine 2. alpha methyldopa 3. tizanidine 4. Apraclonidine 5. Brimonidine

Question 30

How do you treat acute intoxication of amphetamine

Answer 30

1. Ascorbic acid to promote excretion 2. sedatives to control CNS symptoms 3. sodium nitroprusside for hypertension

Question 31

What are the uses of amphetamine

Answer 31

1. Narcolepsy 2. ADHD 3. anorexiant 

Question 32

Which drug causes increased GFR

Answer 32

Dopamine

Question 33

What is the function of Fenoldopam

Answer 33

D1 agonist  used in hypertensive emergencies (decreases BP)

Question 34

Name anorectics (anorexiants)

Answer 34

1. Mazindol 2. Phentermine 3. Sibutramine 4. Orlistat

Question 35

Which drug is able to block reflex bradycardia from alpha-1 agonist

Answer 35

Atropine

Question 36

What are the contraindications of using Parasympathomimetics

Answer 36

1. COPD 2. patients with cardiac disease 3. narrow angle glaucoma