blood brain barrier
maintain microenvironment of brain tissue
regualtion of molecules passing from blood to brain tissue
primary brain injury
damage that occurs at time of trauma
extradural haematoma
collection of blood between skull and outer layer of dura
subdural haematoma
caused by tearing of venous circulation after rapid falls
bleeding between inner layer of dura and arachnoid matter
intraventricular haemorrhage
bleeding into ventricles
acute hydrocephaus
coup and counter coup injuries
coup- direct trauma
counter- opposite to coup where brain hits back of head
aims of medical management
prevent secondary brain injury
manage other injuries
nutrition
prevent further complications such as DVT
SECONDARY BRAIN INJURIES
DUE to hypoxaemia
-changes in BBB permability
decrease or increase in blood supply
increase of pressure
factors that worsen secondary brain injuries
high intracranial pressure
hypotension
hypoxaemia
hypercpania
management of secondary brain injuries
mangae blood pressure
minimise brain metabolism
mechanical ventilation
normal intracranial pressure
7-15
cause of high ICP
increase blood volume in skull
diffuse cerebral oedema
Increase in CSF
increase cerebral blood flow
cerebral perfusion pressure
gradient driving cerebral blood flow
must be maintained between 70-90 mmHg
CPP= MAP-ICP
if CPP is low
low oxygen delivery than
hypoxic brain injury
respiratory effect on cerebral blood flow
hypercpania causes vasoldilation and too much CBF
hypocapnia cause vasoconstriction and too little
aims for post TBI
respiratory aims
musculoskeletal aims
rehab optimise early neurological recovery and function