Gynecological DMS 113 > TEST 3 STUDY GUIDE ECTOPIC PREG & MORALS > Flashcards

TEST 3 STUDY GUIDE ECTOPIC PREG & MORALS Flashcards

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1
Q

ectopic pregnancy:

A
  • Location of pregnancy outside uterus
  • 10% maternal deaths related to ectopic pregnancy
  • Effect on future fertility & recurrance
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2
Q

true or false? A woman capable of conceiving is capable of having a pregnancy in a location other than the uterine cavity

A

true

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3
Q

clinical findings ectopic pregnancy:

A
  • Positive pregnancy test
  • Pain 97%
    • Shoulder, generalized abd, lower abd, lower quadrant ipsilateral to ectopic, lower quadrant contralateral to ectopic, back, vaginal
  • Vaginal bleeding
  • Palpable adnexal mass
  • Clinical Triad – Pain, Bleeding, Adnexal mass – 45%
    • Not specific for ectopic pregnancy – 14% confirmed ectopic
    • Ovarian cysts (27%), PID (15%), DUB (4%), Spont Ab (5%)
  • Present at 5-6 weeks
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4
Q

ectopic prenancy occurs in fallopian tubes in almost __ of patients

A

95%

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5
Q

when ectopic pregancy is located in the _____ portion of the ____ ____ near the ___ ___, an increased risk of massive hemorrhage exists, which may lead to hysterectomy or even death.

A

interstitial

fallopian tube

uterine cornua

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6
Q

true or false?

serum beta hCG levels in an ectopic pregancy do not increase as they do in a normal pregnancy

A

true

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7
Q

what is the clinical triad found w/ ectopic pregnancy?

A

Pain, Bleeding, Adnexal mass – 45%

  • Not specific for ectopic pregnancy – 14% confirmed ectopic
  • Ovarian cysts (27%), PID (15%), DUB (4%), Spont Ab (5
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8
Q

when are clinical findings present for ectopic pregnancy?

A

5-6 weeks

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9
Q

Pregnancy Testing w/ hCG: what is 2IS

A

2IS (Second International Reference)

  • Introduced in 1960’s
  • 800 - 1000 IU/L - normal intrauterine gest sac can be seen
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10
Q

slight risk factors for ectopic pregnancy:

A
  • Previous pelvic/abd surgery (.9-3.8),
  • smoker (2.3-2.5),
  • Vaginal douching (1.1-3.1),
  • early age 1st intercourse <18 yrs (1.6)
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11
Q

Moderate Risk factors for Ectopic Pregnancy:

A
  • Infertility (2.5-21),
  • Previous genital infections (2.5-3.7),
  • Multiple sexual partners (2.1)
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12
Q

High risk factors for Ectopic Pregnancy:

A
  • Tubal Surgery (21.0),
  • Sterilization (9.3,
  • Previous ectopic (8.3),
  • DES daughter (5.6),
  • Use of IUD (4.2-45.0),

Documented tubal disease (3.8-21.0)

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13
Q

Pregnancy Testing with hCG: what is 1st IRP

A

(First International Reference Preparation)

  • Purer standard – main standard used today
    • 1000 - 2000 IU/L - normal intrauterine gest sac can be seen
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14
Q

what is the minimum lwvel of hCG in normal pregnancy?

A

2000 mIU/mL, IRP

  • If no gest sac seen ≥ these levels=suspect ectopic
  • Differential dx -> possible early IUP, miscarriage, ectopic
  • As many as 19% may have IUP on followup
  • Guideline only – use clinical indications and f/u if stable
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15
Q

Serial quantitative beta hCG levels

A
  • hCG levels double every 2 days in normal preg
    • & 21% of ectopic
  • 90% ectopic preg nonviable -> beta hCG levels low
  • Falling hCH levels may indicate missed or incomplete abortion
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16
Q

TRUE OR FALSE?

90% ectopic preg nonviable -> beta hCG levels low

A

true

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17
Q

Falling hCH levels may indicate:

A

missed or incomplete abortion

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18
Q

common sites of ectopic pregnancy

A
  • Tubal 95-97%
    • Ampullary – most common
    • Isthmus – second most common
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19
Q

Uncommon Sites of Ectopic Pregnancy

A
  • Interstitial (Cornual) – rare 2-5%
  • Ovary – rare 0.5 – 1.0% (text states <3%)
  • Fimbria – very rare
  • Cervix – very rare 0.1%
  • Abdominal – very rare
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20
Q

image: sites of ectopic preg

A
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21
Q

A

A

Interstitial (cornual)

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22
Q

B

A

isthmus

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23
Q

C

A

abdominal

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24
Q

***D

A

ampullary

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25
\*\*E
fimbrial
26
\*\*F
Ovary
27
\*\*G
cornual (interstitial)
28
\*\*H
fornix
29
\*\*I
cervical
30
\*\*J
body of uterus
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\*\*K
abdominal peritoneum
32
true or false? a increased risk of a complete hysterectomyexists when an ectopic pregnany is located in the uterine cervix.
33
a combination of ___ \_\_\_ and an ___ \_\_\_ is the best correlation in dagnosis of an ectopic pregnancy.
free fluid; adnexal mass
34
echogenic free fluid is related to a \_\_% risk of ectopic pregnancy.
92% (86%-93%)
35
what are the Sonographic Findings: Ectopic
* **Determine if normal early intrauterine pregnancy** * Intrauterine gestational sac preferably with heart beat * **Extra-ovarian Adnexal mass** * **Fluid in cul-de-sac** * Echogenic fluid (86-93% for ectopic) * Check kidneys for hemoperitoneum * **Pseudogestaional sac** * Differentiate betwn normal IUP & pseudo * 20% ectopic preg demonstrate pseudo gest sac * **Finding of live embryo within adnexa** (specific) * **Extrauterine gestational sac or ring in adnexa** - 71% * **26.3% ectopic preg with a normal sonogram**
36
what is a pseudogestational sac?
located in middle of endometrium, does not have a yolk sac, has internal echoes, and a high resistive spectral waveform
37
**EARLY IUP:** shape, location, margins, decidual reaction, sac
round eccentric location in endometrium well defined margins well defined decidual reaction possible double decidual sac sign
38
**Pseudosac**: shape, location, margins, decidual reaction, sac
ovoid shape cebtral location in endometrium poorly defined margins absent decidual reaction single decidual layer
39
pseudogestational sac characteristics
1. No living embryo 2. No yolk sac 3. Sac central endometrium 4. Low level echos 5. Best seen endovaginal 6. High resistance pattern * (low diastolic flow) with low peak velocities
40
decidual cast - pseudosac
41
gestational sac
**_echogenic ring - classic chorionic ring_** Double decidual sac sign --Inner ring – echogenic chorionic vili --Outer ring- deeper layer of decidua vera (D)
42
gestational sac
Double decidual sac sign plus yolk sac
43
Adnexal Masses with Ectopic
Complex adnexal mass * Extrauterine gest sac * Hematoma within peritoneal cavity * Within fallopian tube or broad ligament * Ovarian Cyst: Corpus luteum cyst * Differentiate with surrounding ovarian tissue * Quantitative beta-hCG levels * 80% with ectopic have @25 ml blood pooling in peritoneum * 60% Intraperitoneal fluid - moderate to large quantities * Check abd gutters to eval extent of fluid present
44
what is the most frequent sonographic finding in an ectopic pregancy?
adnexal mass
45
Pregnancy Testing w/ hCG: what is 1st IRP
1st IRP (First International Reference Preparation) * Purer standard – main standard used today * 1000 - 2000 IU/L - normal intrauterine gest sac can be seen
46
\_\_\_ ___ cysts usually regress and are not seen beyond 16 to 18 weeks, but are commonly seen with ectopic pregnancy
corpus luteum
47
most common mass in 1st trimester
corpus luteum
48
\*\*ectopic preg
Rt adnexal ectopic pregnancy Note: echogenic ring between Right ovary and Uterus - Double white arrows Note: embryo within ring (E)
49
\*\*extraovarian adnexal ring
* Left tubal ring adjacent to left ovary * Lt ovarian corpus luteum cyst * No intrauterine preg seen * Small amount free fluid adjacent to ovary (f)
50
adnexal echogenic ring
Rt adnexa mass with echogenic ring consistent with ectopic gestational sac Ring represents trophobastic Tissue or chorionic villi
51
\*\*Ectopic Pregnancy
corpus luteum cyst on left ovary
52
adnexal mass
ectopic pregnancy with blood around it (found during surgery)
53
ectopic scenario
54
\*\*definitive ectopic
90% do not show heart beat
55
true or false? blood + positive hCG results has 86-93% positive perdictive value for ectopic pregnancy
true
56
assessment of cul-de-sac
* Cul-de-sac should be examined for free fluid * Characterize as simple or complex * Complex (echogenic) is suggestive of blood * Blood + positive hCG results has 86-93% positive predictive value for ectopic pregnancy * May be only TV sonographic finding * Check kidneys to evaluate for hemoperitoneum
57
free fluid in pelvis
intraabdominal blood
58
types of ectopic pregnancy
heterotopic interstitial cervical ovarian abdominal
59
heterotopic pregnancy:
* Increased incidence with ovulation induction * Increased incidence with IVF & embryo transfer * Increased risk bilateral ectopic pregnancy
60
interstitial pregnancy (cornual)
* Most life threatening with parauterine & myometrial vasculature * life threatening hemorrhage * 2% occurance in ectopic pregnancies * Eccentrically placed gest sac with incomplete myometrial mantel surrounding sac.
61
interstital pregnancy
62
cervical pregnancy
* Gestational sac within cervix * May contain spontaneous abortion in progress * Color doppler: eritrophoblastic flow in cervical preg * Increased risk of complete hysterectomy * Uncontrolled bleeding w/ increased vascularity of the cervix * Risk factors: multiparity, prior abortion or instrumentation of cx or endometrial cavity
63
cervical ectopic pregnancy * In past, led to hysterectomy * Result of life-threatening hemorrhage * Current treatment conservative * US guided local potassium chloride injection * Systemic or local methotrexate * Preoperative uterine artery embolization before D&C
* TV scan of sagittal uterus showing cervical ectopic pregnancy * No GS present in endometrial cavity. * Intact GS containing YS present in cervix * Magnified view of GS shows embryonic pole with cardiac activity documented with M-mode tracing
64
ovarian ectopic pregnancy
* Very rare - less than 0.5-1% all ectopic * Textbook states \<3% * Complex adnexal masses may involve or contain ovary - making it difficult to distinguish from other ovarian process
65
true or false? if gestational sac is moving it is a spontaneous abortion in progress.
true color is also an easy way to tell if spontaneous abortion or ectopic
66
true or false? the embryo is attracted to c section scars?
true
67
abdominal pregnancy
* **Pregnancy develops outside tubes within peritoneal cavity** * **Sonographic Findings** * Fetus, placenta, amniontic fluid outside the uterus * Membrane around abdomnal pregnancy very thin - no myometrium * Pregnancy lies close to abdominal wall * **Abdominal pregnancies often fail before term** * **C-section delivery with placenta left in place** * Methotrexate to help reabsorption
68
c section scar pregnancy
69
treatment of ectopic pregnancy
* **Microsurgery through laparoscope to maintain function of unruptured tube** * Linear salpingostomy with milking pregnancy out of distal ampulla * Possible resection of segment of fallopian tube w/ gestation w/ or w/o reanastomosis * **Methotrexate injection - antimetabolite chemotherapeutic agent that interferes with DNA synthesis & disrupts cell multiplication.** * Eliminates morbidity from surgery & general anesthesia * less tubal damage, less cost & need for hospitalization * Patient must return for follow up * Lower success rate w/ ectopic with cardiac activity * **Surgery** * Live ectopic * Large adnexal mass \> 4cm
70
indications for 1st trimester exam
* confirm IUP vs. EUP * define cause of bleeding * pelvic pain * viability * # of embryos * gestational age * detect anomalies * r/o hydatidform mole * adjunct to CVS, amnio, embryo transfer, IUD removal * 1st trimester exam done only when deemed necessary
71
gravidity:
of pregnancies including this one
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parity:
all pregnancies fullterm, premature&stillborn, early loss or abortion, living children. In US P+A= G
73
1st trimester
till 14 weeks (0-14 weeks)
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\*\*2nd trimester
till 27 weeks (14-27 weeks)
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\*\*3rd trimester
27 weeks-term
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2nd and 3rd trimester indications
* gestational age * fetal growth * vag. bleeding * abd/pelvic pain * incompetent cervix * #fetuses * determine fetal presentation * size descrepancies to dates * pelvic mass * r/o ectopic * suspect hydatidform mole * cervical cerclage placement * fetal viability * uterine abnormality * amniotic fluid * evaluate fetal well being * placental abruption * external cephalic version * premature rupture of membranes * abnormal chemical markers -lab values * f/u fetal anomaly * hx prev congenital anomaly * eval for late to prenatal care (cant see bones block view
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maternal risk factors
* Maternal Age * Abnormal triple screen biochemistry values * Maternal disease * Uterus measures large or small for dates * Previous child with chromosomal disorder * Exposure to teratogenic drug or infectious agent * Maternal environment * Nutrition * Genetic
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patient history
* LMP - first day of last menstrual period * EDC determined by earliest ultrasound * Current medications * Clinical problems with pregnancy * Problems with previous pregnancies * Incompetent cervix, fibroids, fetal anomalies * C-section delivery, hypertension
79
safety of ultrasound
* Used in pregnancy since 1950’s - no side effects * exisiting studies not large enough to document small increases in normally occurring anomalies * Studies in animals have suggested: * Growth differences * Increase in left handedness * Delayed speech
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Obstetrical US factors
* Theoretical effects of US energy on fetus has potential biological effects not yet documented * Energy produced by US equipment today is higher than that produced by earlier units * Doppler imaging produces higher energy * Study of US bioeffects are not definitive- continued research is essential * Sonographers have responsibility to be knowledgeable about US bioeffects and use the least amount of energy necessary to produce clinical information needed.
81
biologic effects
* Thermal - a rise in temperature * Minimize thermal effects * Don’t stay in one spot for long period of time over bone * Extend focus of beam deep for adequate image * Cavitation - production and collapse of gas filled bubbles * Dependent on the presence of gas preexisting within tissue * Neonatal lung
82
guidelines for US exam
* Examination protocol * AIUM guidelines * Qualification of personnel * National board certification * Documentation standards * Patient name, date, image orientation * Written report in patient records * Equipment * Transducer frequency selection * ALARA- (as low as reasonably achievable) principle * Safety * HIPAA, Infection control, Quality control, * Musculoskeletal injury - ergonomic protection
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informed consent is an ____ based right
autonomy
84
what did thomas percival do?
changed medical ethics * Redefined patient as anyone needing care. * Team approach in health care and public health * Needs of patient came over competition or professional interests
85
Hippocrates said what and what does it mean?
"First do no harm" * ethical principle of nonmaleficence * emphasized tmts based on best benefit to patient * treat pt like you would your own family
86
what emphasizes individual rights and autonomy, which has beecome a key element in modern day ethics
Nuremberg Code -came from experimenting on prisoners basic principles put into research , professional codes and clinical practice throughout the world
87
basic principles of ethics
* autonomy * justice * beneficence * nonmaleficence * integrity * respect for persons
88
\_\_\_ethics serve as a foundation for ___ ethics
philosophic medical
89
ethics
* **systematic reflection on and analysis of morality** * **s**tuy seeks to articulate clear, constant, coherent, and practical guidelines for conduct and character
90
nonmaleficence
cause no harm education, competency, skill, impressions are appropriate
91
which principle directs the sonographer not to cause harm
nonmaleficence principle
92
beneficence:
**seeks greatest benefit from exam** the goal seeking a greater balance of _clinical goods_ over _clinical harms_
93
integrity:
ino difference exists in what a person says and what he or she does
94
primum non-nocere (first do no harm)
stresses choosing a treatment based on the best benefit to the patient
95
pain
physiologic phenomenon involving the central nervous system processing tissue damage
96
morality
**reflects duties and values &** **matters concerning right and wrog conduct and good and bad character**
97
confidentiality:
**of HIPPA** **from principle of beneficence** **pateint spouse and familes are third parties** **no info given w/out pt explicit permission** the job of the healthcare professional to protect and respect a patients privacy
98
**\*\*HIPPA practices conform to what principle of medical ethics?**
confidentiality of findings
99
\*\***continuing ed is an ex. of what principle of ethics?**
non-maleficience
100
true or false? SDMS has adopted a code of ethics for medical sonographers?
true
101
what type of issue is family tradition?
moral issue
102
providing a detailed explanantion of the exam is an ex. of what principle of ethics?
autonomy
103
integrity
adhering to moral and ethical principles
104
reading current medical literatures, and being aware of new developments is an ex. of what principle of ethics?
nonmaleficience
105
the principle of \_\_\_\_\_\_requires sonographers to preform only medically indicated examinations and to perfor all examinations in keeping with ALARA to get desired results
nonmaleficience
106
veracity:
truthfulness
107
justice:
**fair ditribution of benefits and burdens** sonographers must thrive to treat all pateints equally
108
\_\_\_\_ encourages sonographer to go beyond the minimum standard protocol and to seek additional images and info if achievable and in the best interest of the patient
beneficence
109
principle of ____ obligates the sonographer to seek the greates benefit for the pt
beneficience
110
autonomy:
**key ethical principle is the right to self-determination, patient right to refuse, right to information (1st trimester scan for abortion)** self governing or self directing freedom to choose and have their decision respected
111
an obligation to the fetal patient going to term to protect and promote both fetal interests and those of the child it will become as understood from a rigorous clinical perspective ai what principle of medical ethics?
beneficence
112
which ethics principle requires sonographers to perform all examinations with ALARA
nonmaleficence
113
true or false? info receivewd from a sonogram enhances a woman's choice or _autonomy_, and failure to provide these choicesw to some women and not others is an example of _injustice._
true
114
truthfullness w/ respect to abilites and limits is an example of \_\_\_\_
veracity
Gynecological DMS 113
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