bitters
found in:
activate taste receptors -> secretion of salvia gastric acid and chole -> improve digestion (30min before meal)
bitterness determination:
types of drugs containing bitters
type depends on helper compound type
great yellow gentian
gentiana lutea
centaury
centaurium erythtea
wormwood
artemisia absinthium
arnica
arnica montana
st. benedicts thistle
cnicus benedictus
artichoke
cynara scolymus
dandelion
taraxacum officinale
terpenoids - diterpenes
C20
regulate plant growth
many toxic, medicinal agents
white horehound
marrubium vulgare
triterpenes
C30
phytosterols
steroid-glycoalkaloids
saponins
cardiac glycosides
cardiac glycosides
faster and more powerful heart contraction
2 types: bufadienolide and cardenolide
cardenolides
hydrophilic(sugar) and hydrophobic(steroid) part
5 member ring
dont use as home remidy –> specific dosage, toxic if wrong
spp. digitalis
foxglove spp.
saponins
emusifying effect: hydrophobic and hydrophillic part
foam in rumen
hemolysis
disintegrated cell membranes
cowslip
primula veris
fenugreek
trigonella foenum
ginseng
panax ginseng
liquorice
glycyrrhiza glabra
pot marigold
calendula officinalis