what is related with increase neutrophils
- neutrophila
- leukocytosis
- infection
- inflammatory
what is related with decrease neutrophils
- neutropenia
- marrow depression
- viral infection
- autoimmune disorders
what is related with increase of eosinophils
- allergic reaction
- parasitic infection
- skin disease
- neoplastic disease
what is related with a decrease of eosinophils
- cushing’s
- stress
what is related with increase basophils
- CML
- Ulcerative Colitis
what is related with decrease basophils
- least common granulocyte
what is related with increase lymphocytes
- viral infection
- autoimmune disorder
- mono
- lymphatic leukemia
what is related with decrease lymphocytes
- defective lymph circulation
- high corticosteriod levels
what is related with increase monocytes
- subacute bact. endocarditis
- disseminated TB
- monocyte leukemia
- Rheumatoid collagen disease
what is related with increase hematocrit
- polycythemia
- dehydration
what is related with decrease hematocrit
- anemia
- hemorrhage
what converts prothrombin to thrombin
- thromboplastin
what converts fibrinogen to fibrin
- thrombin
what is related to increase fibrinogen
- cancer
- inflammatory
- oral contraceptive
- pregnancy
what is related to decrease fibrinogen
- DIC
- Burns
_ acture sever bleeding
what are some symptoms with iron def. anemia
- parethesia
- burning tongue
- cracking at mouth
- gastritis
what is related with iron def. anemia
- hypochromic
- microcytic
- target cells
what are the blood values with iron def. anemia
- MCV is low
- MCHC is low
- HCT is low
- Hb is low
- leukocytes unaffected
- thrombocytosis
what occurs when BJ proteins are found in urine
- abnormal growth of plasma cells
- multiple myeloma (50%-80%)
- chronic lymphocytic leukemia
- lymphoma
- metastic lytic bone lesions
- Waldenstrom’s macroglobulinemia
- end - stage of renal failure
- amyloidosis
what occurs with multiple myeloma
cancer of plasma cells, type of WBC normally responsible for producing antibodies
- collection of abnormal plasma cells accumulate in the bone marrow - interferes with normal RBC production
what are the common symptoms with multiple myeloma
Calcium
Renal failure
Anemia
Bone lesions
name some manifestations of multiple myeloma
- bone pain
- low counts RBC, WBC, platelets
- Kidneys cane be damaged by tubulopathic effects of proteins or BJ light chains
- stroke like
- numbness, weakness
