Describe the electrophysiological basis for impulse generation, conduction and the ECG.
Two adjacent cells with different charges creates a dipole. This dipole has a direction (ie. a vector) so the orientation of the dipole matters, as does the position of the electrodes.
Placing a lead with a reference end and a sensor end can read the direction and magnitude of this dipole.
The body is a good conductor. Depolarisation of the heart involves many more cells than just 2 adjacent myocytes. The spread of depolarisation involves many dipoles that are oriented in different directions simultaneously. The voltage that is detected at any instant results from the net dipole that = sum of all of these vectors.
Remember that the position (i.e. direction) of the electrodes matters.
Describe the basic components of the ECG waveform and normal values of the major intervals.
P wave: atrial depolarisation.
QRS complex: collectively ventricular depolarisation
T wave: ventricular repolarisation
PR interval (0.12-0.2s)
RR interval
QT interval (<0.44s men, <0.46s women)
QRS complex duration (<0.1s)
ST segment
Relate the orientation of the ECG leads to the electrical events that occur in the heart
We are able to superimpose the limb leads over the heart to give an axial reference system.
There are an extra 6 chest leads that allow us to look at the heart in three dimensions
Basic 3 lead ECG
Forms a triangle called Einthoven’s triangle.

Augmented limb leads
Inferior leads
aVF, II and III
Lateral leads
I, aVL, V5 and V^
Anterior leads
V1-V4