Functional unit of the thyroid, and what do they make?
Thyroid Follicular Cells (make thyroglobulin)
Types of hypothyroidism
Primary - issue with thyroid
Secondary - issue with Pituitary or hypothalamus
Most common cause of primary hypothyroidism worldwide
Iodine deficiency
Most common cause of primary hypothyroidism in US
Hashimoto’s
Causes of primary hypothyroid
Autoimmune
- Hashimoto’s
- Postpartum
- Riedel’s
Iodine deficiency
Infectious
Iatragenic
Antibodies produced in Hashimoto’s
Anti-Thyroglobulin (“Anti-TG”) antibodies
Anti-Thyroperoxidase (“Anti-TPO”) antibodies
Most common cause of infectious hypothyroid
Upper respiratory tract infection