by which mechanism is the hypothalamo-pituitary-thyroid axis controlled
negative feedback
what do T3 and T4 have direct negative feedback over
thyrotroph cell in anterior pituitary by reducing TSH release
what do T3 and T4 have indirect negative feedback over
hypothalamus by reducing TRH release
what effect does iodide have on the thyroid (Wolff-Chaikoff effect)
suppresses release of T3 and T4
what do oestrogens do to TSH release in anterior pituitary
stimulate
what do glucocorticoids do to TSH release in anteror pituitary
suppress
diagram of hypothalamo-pituitary-thyroid axis
diagram