*** Urinary Flashcards

(47 cards)

1
Q

Cortez et al Vet Surg 2024-

Of the 12 cats, how many had:

Ectopic ureters?

Bilateral?

Immediate PO complications?

Complete resolution?

A
  • Ectopic ureters (8/12; 66%)- Extramural
  • Bilateral (6/8- 75%)
  • Immediate postoperative complications occurred in 3 cats (25%)- urethral spasm (treated medically); progressive hydroureter/hydronephrosis (resolved without intervention) and progressive urinary incontinence which resolve without additional treatment
  • Complete resolution in 11/12; (92%)
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2
Q

Andrews et al JAVMA 2024-

What has the frequency of cystine and urate stones visible on radiographs in dogs?

A

86% urate
92% cystine
100% urate/cystine

*** Contrary to previous beliefs that they were radiolucent or marginally radiopaque

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3
Q

Nash et al JAVMA 2023-

Evaluated tube cystostomy for urinary outflow management in dogs with IVDE and ischemic myelopathy cranial to L3 spinal cord segment.

What % of owners reported tube cystotomy was easy and very easy to use?

When was the median time to removal?

Complication rate?

A
  • 81%
  • 19 days
  • Overall complication rate- 38% (71% minor; 29% severe); The most frequent
    complication was inadvertent dislodgement of the
    cystostomy tube by the dog following discharge. The second most frequent complication was
    peristomal urine leakage.
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4
Q

Gibson et al JAVMA 2022-

How many procedures was a urinary implant successfully retrieved via endovascular snare system?

Complication rate?

Intraoperative complication rate?

A
  • An ESS was used successfully for removal or re-
    positioning of urinary implants, including ureteral
    stents or retained urinary catheters for 18 procedures in 14 dogs and 3 cats
  • No patients
    developed any known complications associated with
    use of the ESS, further supporting this as a safe alter-
    native to more invasive procedures
  • One procedural complication (5%) was reported in the
    present study. This complication occurred during the attempted retrieval of a retained vesicourethral im-
    plant in a male dog. The implant, which had been se-
    cured within the ESS, became dislodged at the pelvic
    flexure on withdrawal. The stability of the interlocked
    snare device requires close association of the snare
    wire to the catheter, which is maintained by counter-
    tension between the snare and catheter. Suboptimal
    tension by the operator likely led to loss of this connection with resultant dropping of the implant in the distal portion of the urethra before removal.
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5
Q

Job et al JVIM 2022-

What is the difference between percutaneous cystolithotomy and open cystotomy in dogs and cats in regards to:

  • Anesthetic and surgical time?
  • Safety?
  • Efficacy?
A
  • No significant difference regardless of species (mean surgical time 45 PCCL vs 48 OC min; mean anesthetic time 90 PCCL vs 98 OC min)
  • PCCL can be safely and efficiently performed in dogs and cats regardless of weight, sex and with any number of uroliths.
  • Complete urolith removal was achieved in 98% of dogs and cats by PCCL
  • The median hospitalization time was significantly shorter in the PCCL group for dogs but did not differ in cats

-There were no major intraoperative complications in the PCCL group, with no need for conversion to an OC

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6
Q

Duval et al JFMS 2022-

When using 4% tetrasodium EDTA (tEDTA) in obstructed SUBs what was the:

Success rate?
Recurrence of obstruction rate?
Time to recurrence?
Clinical signs post-infusion?

A
  • 69%
  • 55%
  • 87 days
  • One or more episodes of self-limiting pollakiuria and/or hematuria following infusion was seen in eight patients (n=8/14; 57%)
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7
Q

Boone et al Vet Surg 2025-

Comparing modified percutaneous cystolithotomy (mPCCL) to open cystotomy (OC), what were the findings?

A
  • mPCCL had smaller incisions and shorter hospitalizations but had no other clear advantages
  • Incisional infections were associated with hospitalization duration in the OC group
  • Incomplete urolith removal was associated with increased surgical time when no additional procedures were performed in the OC group.
  • For PCCLm, incomplete urolith removal was associated with lower urinary tract signs within 14 days postoperatively, increased incision length, anesthesia time, and hospitalization duration.
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8
Q

Covo et al JFMS 2024-

In cats with malignant causes of ureteral and/or urethral obstruction how did SUB vs self-expanding metallic stent compare?

What was the MST in these cats?

A
  • Repeat urethral obstruction due to tumor in growth occurred in 6/13 cats with a SEMS (46%), and no cats developed recurrent ureteral obstructions after placement of the SUB device. 3 cats had additional covered stents placed after urethral re-obstruction.
  • 52 days in cats with ureteral obstruction with or without concurrent urethral obstructions, 80 days with urethral obstruction alone.
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9
Q

Habib et al JVIM 2025-

Assessing ureteral patency by fluoroscopy and ultrasonography after subcutaneous ureteral bypass device placement for the treatment of benign ureteral obstruction in cats…..

What was the incidence of native ureter recanalization?

Of the cases that had patent ureters, what were the causes of obstruction?

What is the Sn/Sp for ureteral patency for observation of a trigone irrigation during ultrasound guided irrigation?

A

19/23 cases (83%) evaluated were patent on fluoroscopy ranging from 1 month to 6 years after surgery

16/20 patent ureters were obstructed with ureteroliths (80%) and 3/3 with presumed stricture (100%)

Observation of a trigone irrigation during routine ultrasound-guided SUB irrigation is a reliable indicator of ureteral patency, with a specificity of 100% and sensitivity of 88%

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10
Q

Price et al JVIM 2025-

What % of polypoid cystitis cases were identified incidentally?

Where were the polyps identified?

What % had recurrent UTI signs?

What % had BRAF V595E mutations?

What were the common bacteria isolated in dogs with UTIs?

A
  • 12%
  • 80% cranioventral bladder apex
  • 20%
  • 0%
  • Escherichia coli (53%), Enterococcus faecalis (19%) and Staphylococcus pseudintermedius (7%)
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11
Q

Schultz et al JVIM 2024 -

In regards to renal biopsy:

What disease had the shortest survival time?

Which risk factors were associated with an increased risk of death?

A
  • Renal amyloidosis - MST 76 days vs 608 days overall
  • Age, serum creatinine, serum albumin, and UPC
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12
Q

Adair et al VetSurg 2023-

Comparing modified percutaneous cystolithotomy and open cystotomy:

Which had the longest anesthesia time?

Which had the longest surgery time?

What is the total conversion rate of PCCLm to open cystotomy?

What factor was associated with remaining cystoliths on post-op radiographs in the PCCLm group?

Was PCCLm associated with an decreased risk of leaving stones?

A
  • Open cystotomy group
  • Neither
  • 4% (5/131)-
    ** 4 cases of conversion were due to too numerous stones and difficulty retrieving them with the cystoscope
    **
    1 case was due to extensive hemorrhage of the spleen following laceration upon entry into the abdomen

Post-op radiograph stones:
1. Lower urinary tract obstruction on presentation (5x more likely)
2. Presence of a large, firm bladder on PE (13.5x more likely)
3. Larger body weight (5.6% more likely with each additional kg of weight)
4. Uroliths too numerous to count on preoperative radiographs (3.92 x more likely)
5. Anesthesia time (2.5% more likely with each additional minute)
6. Surgery time (2.1% more likely with each additional minute)

  • No

** The only factor significantly more likely to cause the outcome variable of SSII within 14days, was extension of the incision to gain improved exposure and not for additional procedures in the PCCLm group (17.87 times more likely
**
Significantly reduced postoperative lower urinary tract signs were noted in the PCCLm group

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13
Q

Aronson et al JAVMA 2022-

In pre-renal transplant cats:

What CV abnormalities were identified?

Did these abnormalities affect survival?

What factor was found to affect survival?

A
  • Hypertension, murmur, echo changes, CHF
  • No
  • Age (risk of death increased 11% for every 1 year)
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14
Q

Bohlen and Nickel JSAP 2022-

When placing an artificial urethral sphincter in males:

What % achieved short term continence?

What % remained continent long term?

Minor complication rate?

Major complication rate?

A
  • 84%
  • 53%
  • 25% (Mild complications= Hematoma, stranguria/temporary dyssynergia and mild inflammation at the port)
  • 31% (Major complications= Obstruction, dyssynergia, fistula at port and port rotation)

***Overall complication rate of 56%

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15
Q

Buote et al JFMS 2022-

Did this paper support the use of minimally invasive surgery to remove cystoliths in cats?

A

Yes- they had lower pain scores, returned to eating more consistently, and were equally likely to have stones left behind

  • The primary outcome measure was a composite outcome score, including three variables: pain scores ⩾2 at either 6 or 12 h postoperatively; failure to remove all stones as determined by postoperative radiographs; and postoperative complications requiring a visit to the hospital separate from the planned suture removal appointment
  • The cats in the open surgery group had 8.3 times greater odds of developing the composite outcome than cats in the MIS group
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16
Q

Friday et al Vet Surg 2023-

What % of renal transplant cats had metastatic calcification pre-op?

Developed it post-op?

What was associated with the cases of metastatic calcification detected pre-op?

A
  • 20%
  • 16%
  • Shorter mean survival time (147 days; without- 646 days) and a 240% increase risk of death

** For every 10 mg/dL increase in BUN, the odds of developing calcification post-transplant were 1.45 times higher than those with lower pre BUN values
**
The most common location of metastatic calcification involved vascular structures
*** Metastatic calcification in renal transplant cats is a negative prognostic indicator and is associated with decreased survival times

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17
Q

Hammond et al JVECC 2022-

Was the use of balloon dilation successful in the management of pelvic urethral strictures?

A

Yes - The strictures in all 3 cases were successfully treated with a combination of fluoroscopic-guided balloon dilation and short-term indwelling urethral catheterization while managing any present infection.

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18
Q

Hardie et al Vet Surg 2023-

What was the main difference between the simple nephrocystostomy (NCTs) and bladder cuff nephrocystotomy technique for ureteral bypass in cats?

A

All simple NCTs became obstructed after catheter removal versus bladder cuff NCTs remained patent for 90 days

*** For simple NCT, an 8F catheter was placed through the caudal pole into the renal pelvis and the bladder was sutured around the catheter

*** For bladder cuff NCT, a 6 mm defect was removed from the caudal pole and a cuff of bladder mucosa was advances and sutured into the renal pelvis. A 10 F catheter was placed through the defect into the renal pelvis and the bladder wall was sutured around the catheter.

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19
Q

Hart et al Vet Surg 2021-

When performing transperitoneal laparoscopic ureteronephrectomy for renal neoplasia:

What was the complication rate?

PFI?

A
  • No major perioperative complications occurred and all dogs survived to discharge
  • Progression free survival- 422 days

*** Open ureteronephrectomy should be considered in cases with largest mass diameters >8 cm and estimated ellipsoid volume >127 cm^3

*** Previously published data in dogs on case selection had estimated that masses with a diameter of <6 to 7 cm in dogs >15 kg without extension beyond the renal capsule could be considered for removal by TLU

20
Q

Johnson et al JAVMA 2024 -

In dogs with renal disease getting nephrectomies:

Intra-op complication rate?

PO complication rate?

What risk factors were NOT identified in developing chronic kidney disease PO?

A
  • 45%
  • 43%
  • Postoperative acute kidney injury and NSAID administration were not statistically associated with the development of chronic kidney disease in this population

** 40% of dogs in this study had complications secondary to hemorrhage associated with renal dissection
**
Severe hemorrhage, considered as loss of >15% of blood volume, was noted in 8.7% dogs with all receiving an intraoperative blood transfusion

*** Few dogs in this population had GFR measured preoperatively and an abnormal GFR was not associated with increased risk of CKD development long-term

*** Chronic kidney disease was diagnosed in almost 50% of the population with available long-term follow up

21
Q

Oyamada et al Vet Surg 2023-

In cats with extravesicular, 2-layer, side-to-side ureteroneocystostomy combined with tension relieving technique for proximal ureteral obstruction:

Survival rate?

PO BUN and Creatinine?

Perioperative complications?

UTI rate?

A
  • 100% (All cats survived through discharge)
  • In all cats, postoperative BUN and CREA concentrations were decreased compared with preoperative concentrations
  • Perioperative complications included ureteral catheter dislodgement (3; 30%), transient pollakiuria (2; 20%) and dysuria (1; 10%), but no specific treatments were required
  • 30% (3/10)

** 7 of the 10 cats (70%) were alive without recurrent ureteral obstruction at the end of this retrospective study
**
A novel form is called extravesicular two layer side to side ureteroneocystostomy combined with tension relieving techniques (ETSUTT), which consists of a modified extravesicular technique and 3 different tension relieving techniques (ie: renal descensus, ureterocystopexy and nephrocystopexy)

22
Q

Reyes and Scharf Vet Surg 2023 -

Was laparoscopic partial cystectomy sealed with endoscopic GIA stapler feasible in canine cadavers?

A

Yes- Laparoscopic partial cystectomy was successfully performed in 10 of 11 cadavers (91%)

** Median procedure time was 13.6 minutes
**
Median intravesical pressure at initial leakage was 31 mmHg with a median increase from initial pressure of 15 mmHg
*** No catastrophic failure of the cystectomy site was observed during leak testing

23
Q

Song et al Vet Surg 2024:

What was CTs ability to identify normal ureters correctly?

What was CTs ability to identify ectopic ureters correctly?

Sensitivity of identifying extramural vs intramural ureters?

Specificity of identifying extramural vs intramural ureters?

A

Determine receiver operating characteristics (ROC) of CT excretory urography in predicting cystoscopic findings of ureteral anatomy.

  • 50%
  • 78%
  • Sn= 29% extramural vs 65% intramural
  • Sp= 97% extramural vs 71% intramural

*** CT did not accurately predict anatomy of ureters; CT findings may need confirmation by cystoscopy and possibly intraoperative fluoroscopy prior to determining if CLA is indicated or not

24
Q

Mickelson et al Vet Surg 2021-

What device was evaluated for renal transplant vascular anastomosis?

Using this device for feline renal transplants….
Was an end-to-side anastomosis of the renal vein and vena cava/renal artery and aorta feasible?

Surgery time compared to hand sewing?

A
  • Microvascular anastomotic coupler (MAC)- 3.5 mm for vena cava (purple); 1.5 mm for aorta (blue)
  • Yes, it was successful in all cats (6/6) with negligible intra-operative hemorrhage
  • 1/2 the time of hand sewing

*** 1/6 (17%) euthanized due to post op hemoabdomen

*** Renal perfusion and resistive index (RI) within normal range 5/6 (83%), similar to the contralateral normal kidneys

*** Advantages of the MAC identified in this study include the overall technical ease of performing the anastomosis itself, shorter duration of anastomoses, negligible hemorrhage from the anastomosis site, and excellent vessel patency

*** Potential complications unique to the MAC include thinning of the vessel wall and focal stenosis at the site of the coupler.

25
Monnet and Hafez Vet Surg 2023- Conventional (C) versus unidirectional barbed suture for canine vesiculourethral anastomosis for prostatectomy: - What was the difference in leakage pressure? - Which was faster?
- The leakage pressures were statistically similar in both groups (no difference) --> However, biologically the risk of urine extravasation is more likely increased with unidirectional barbed sutures since the leakage pressure of the VUO was 28% lower in the unidirectional sutures than with conventional sutures - Unidirectional barbed suture-The median suturing time was 12.7 minutes for the UBS group and 17.3 minutes for the C group (reduced by 25%) *** Unidirectional barbed suture does not statistically affect the acute leakage pressure of VUA in normal cadaveric specimen *** It resulted in a shorter surgical time and fewer suture bite placements
26
Bentley et al 2023- What ultrasound finding was evaluated in this study and were they associated with pathology?
- Renal Medullary Striations - Medullary striations are associated with proteinuria and urinary tract inflammation in cats, which may reflect renal tubular dysfunction and/or inflammation
27
Slinkard et al JFMS 2023- What were the imaging features of renal ectopia and fusion in cats?
- Of the 13 cases, 7 were left to right fusions (54%), 4 were right to left fusions (31%), 1 was on the midline (8%) and 1 was in the pelvic inlet (8%) - Classifications of the kidney shapes- lump kidneys (most common), disc kidneys, horseshoe kidney, caudal ectopia, L shaped and pelvic kidney - In 2/13 cases (15%), additional congenital malformations were noted, including an azygous continuation of the caudal vena cava and a peritoneal-pericardial diaphragmatic hernia
28
Woerde JFMS 2025- What marker was evaluated in cats with ureteral obstruction and healthy cats?
Serum galectin 3 (lectin protein present in renal tubules in mice) - Mean serum galectin-3 was lower in healthy cats (274 pg/mL) than in cats with ureteral obstruction (707 pg/mL) - There was no difference in serum galactin 3 concentrations between cats with unilateral or bilateral ureteral obstruction and no correlation between serum galactin 3 and creatinine, body weight or age - With a cutoff of 500 pg/mL, serum galactin 3 had a sensitivity of 86% and specificity of 100% for differentiating cats with ureteral obstruction from healthy cats
29
Merindol et al JVIM 2023- What were the outcomes with medical management in cats with benign ureteral obstruction?
- The causes of obstruction were uroliths in 73%, strictures in 14% and pyonephrosis in 14% of affected kidneys - Outcome after medical management was considered a success in 30%, partial success in 13% and failure in 57% of kidneys - The only factor associated with outcome by cat was age- cats with successful outcome (mean 4 years) were significantly younger than cats with failure outcome (median age 8 years) - Median time to a successful outcome was 16 days - Distal and small (<1-2 mm) uroliths were significantly associated with success
30
Berent et al JVIM 2025- What infusion was evaluated for SUB flushes? Long term outcome?
2% tetrasodium ethylenediaminetetraacetic acid (tEDTA) Group 1= Cats flushed routinely with saline only Group 2= Saline and then switched to 2% tEDTA during their follow-up period Group 3= 2% tEDTA only - Device mineralization was documented in 32%, 50% and 19% SUB devices in groups 1, 2 and 3 - Exchange was needed from re-obstruction in 4/28 (14%), 5/16 (31%) and 3/51 (6%) - Chronic UTI occurred in 7/21 (33%), 4/12 (33%) and 1/33 (3%) of cats --> UTI at the time of surgery was associated with the development of a chronic UTI *** Overall 2% tEDTA had a lower risk of mineralization, re-obstruction requiring exchange and lower chronic UTI's
31
Dekerle et al Vet Surg 2022- What were the outcomes for dogs treated for ectopic ureters with open surgery or cystoscopic guided laser ablation?
Total of dogs in the study= 25 *** Open surgical correction included 13 neoureterostomies, 2 neocystoureterostomies, and a combination of these in 2 dogs. *** Eight dogs underwent CLA. - Eighteen dogs experienced minor complications (72%), and 2 experienced major complications (8%). - One-month postoperative continence was achieved in 20/25 (80%) dogs. - Overall, dogs remained continent for 66 months (median) and 22/25 (88%) dogs achieved continence with adjunction of medical/surgical treatment in incontinent ones. - Fewer minor complications and postoperative recurrences of incontinence were documented after CLA than neoureterostomy
32
Hoey et al Vet Surg 2021- What were the long term outcome of female dogs treated for intramural ectopic ureters with cystoscopic guided laser ablation?
- Continence scores increased in all dogs after cystoscopic guided laser ablation with an increase of the median score from 2 (preprocedure) to 10 (postprocedure) - A urethral tear occurred in 2/34 dogs (~6%) immediately after the procedure, successfully managed conservatively - Mild hematuria was present in 2/34 (~6%), lasting less than 48 hours - Postoperative urinary tract infections were documented in 6/34 dogs (18%) - Complete and near complete urinary continence (scores 9 and 10/10) was achieved in 26/32 dogs (81%) including 3 dogs requiring medical or surgical interventions - 63% of dogs in this study achieved complete urinary continence (score 10/10) - Post-CLA neutering did not affect continence score
33
Jacobson et al JAVMA 2022- What was the modification described in the study for cystoscopic management of intramural ectopic ureters?
Cystoscopic guided scissor transection of intramural ectopic ureters. Safe alternative from laser ablation.
34
Russell et al JAVMA 2024- Golden Retriever dogs following laser ablation of intramural ectopic ureters with a historical urinary tract infection- Short term urinary continence? Long term urinary continence? Negative prognostic indicator for having persistent urinary incontinence?
- 46% - 63% - Presence of historical urinary tract infections was negatively prognostic
35
Canejo Teixeira VRU 2025- What was used to identify urolith composition through abdominal radiographs in dogs?
Artificial intelligence algorithm via a smartphone application (MN Urolith Application) - The algorithm provides the probability of a urolith being composed of struvite from an image taken of an abdominal radiograph - Agreement between the application and quantitative analyses was 81% - These results suggest that the CALCurad can effectively be used to predict urolith composition in dogs, helping the clinician to decide between medical and surgical management of the patient
36
Lea et al JSAP 2024- What technique was evaluated with low profile cystostomy tube placement in dogs? - Success? - Median duration for tubes?
- Single-step, non-surgical placement of a permanent low profile cystostomy tube - Successful in 8 out of 10 dogs (80%), with placement being unsuccessful in two thus necessitating celiotomy (20%) - The median duration the low-profile cystostomy tubes were in place was 7 months *** 7 out of 8 dogs required replacement of their cystostomy tube (88%) *** Mean time until first tube replacement was 103 days *** Lack of cystopexy does not appear to result in complications
37
Centrall et al JFMS 2025- In regards to cystoscopy assisted urolith retrieval via a perineal urethrostomy stoma in male cats (cadaver study and then 2 client owned cat trial)- Procedure time? Success? Results in the two client owned cats?
- The cystoscopic assisted urolith retrieval via PU (CUPU) median procedural time was 13.2 minutes - All (100%) synthetic calculi were successfully retrieved from the 14 cadavers --> Scope associated tearing of the urethra or surgical site was not observed in any cadavers 2 client owned cats with struvite urolithiasis associated urethral obstruction underwent a PU followed by CUPU - All uroliths were successfully retrieved and periprocedural complications were not observed - Both cats had normal stoma sites 4 weeks postoperatively and neither cat had owner reported dysuria 3 months postoperatively
38
Muehlbauer et al JVECC 2023- What was used to evaluate urinary bladder rupture in animal cadavars? Sn/Sp? Accuracy?
- Agitated saline as contrast agent in a contrast enhanced cystosonography (microbubble contrast) - Sn 89%; Sp 100% - Accuracy of 94%
39
Greenfield et al JVIM 2025- What adjunctive treatment option was used in dogs with idiopathic functional outflow tract obstruction? Overall outcome? Complications?
- Percutaneous cystostomy tube - Dogs with cystotomy tubes had better outcomes (71% had good-excellent) but also had mild (100%), moderate (71%) and severe (71%) complications reported - Tube complications were categorized as either mild, moderate or severe *** Of the 7 dogs managed with a cystotomy tube, 7/7 (100%) had mild complications include loose suture, leaking around the stoma and stoma inflammation *** 5 of 7 (71%) dogs were considered to have moderate complications including inadvertent tube removal by the dog which did not require replacement and chronic UTI’s as defined above *** Severe complications occurred in 5 of 7 (71%) dogs including tube dislodgement, requiring immediate replacement and leaking of urine around the tube resulting in a uroabdomen requiring a tube exchange
40
Jareonsuppaperch et al Vet Surg 2024- What graft technique was used in 5 male dogs with penile urethral stricture at the bulbus glandis?
Buccal mucosal graft urethroplasty The 5 dogs recovered well following surgery and only 1 dog experienced a minor complication (20%) *** The one dog experienced bruising and swelling in the surgical area, including the penis, which healed well within 2 weeks - All dogs were able to urinate normally after catheter removal (100%) - No evidence of leakage was identified on a 14 day postoperative retrograde positive contrast urethrogram and clinically at a median follow up time of 182 days - All owners scored the urinary function as excellent and ranked their satisfaction very high 6 months after the procedure
41
41
Manchester et al JAVMA 2024- What was found to be associated with lower urinary tract tears in cats with urethral obstruction? Prevalence of lower urinary tears in UO cats? Prognosis for cats with lower urinary tears?
- Difficult catheterization and previous urethral obstruction (cats with tears also had a higher Hct than the control urethral obstruction cats) - 0.92% - Cats with lower urinary tears were significantly less likely to survive to discharge and had a longer period of hospitalization than cats without tears
42
Wang et al JFMS 2024- What oral medication administered to determine its effects on urethral tone? What were the effects on blood pressure and urethra?
Tamsulosin (selective alpha 1 adrenergic antagonist- newer generation) ■ It has been shown to have better uroselectivity and lower incidence of hypotension compared with other alpha 1 adrenergic antagonists, such as prazosin - Significant changes in blood pressure on day 4 and on day 10 compared with day 0 were not detected in anesthetized cats - No significant difference in maximum urethral closure pressure, functional area or functional urethral length measurements were detected among baseline, day 4 and day 10 of treatment - Hematuria and transient pollakiuria were induced in two cats with 3.5 Fr urethral catheters Tamsulosin at 0.1 mg/kg PO Q24H did not induce hypotension in healthy cats
43
Conway et al JAVMA 2022- What effects did Prazosin administration have on cats treated with urethral obstruction?
- Within 14 days, a significantly higher proportion of prazosin-treated cats (73/302 [24%]) developed a recurrent UO compared with the proportion of non–prazosin-treated cats (and 11/86 [13%]). - The perception of a “gritty feeling urethra” or difficulty of performing the catheterization was associated with increased risk of rUO.
44
Sampaio et al JFMS 2022- What was found to not be associated with early onset urethral obstruction in cats?
Neutering - Intact cats had a significantly earlier onset of urethral obstruction compared with prepubertal and postpubertal neutered cats, as seen by the age at obstruction (3.6 vs. 5.7 and 5.5 years) - Similar clinical signs and histopathological lesions were observed in all groups - The main clinical signs observed were stranguria, hematuria and pollakiuria - All cats had some degree of injury in the penile urethra- the most common lesions were hemorrhage, fibrosis and congestion
45
Yippaditr JAVMA 2022- What treatment can be considered in male cats with traumatic complete urethral rupture?
Buccal mucosal graft urethroplasty ● 13 cats (87%) recovered well following surgery, with no complications in the oral cavity or surgical site and no signs of difficulty or discomfort when urinating ● Urethrography 2 weeks and 6 months after surgery revealed no stricture or leakage in the abdominal cavity ● The 2 remaining cats (13%) developed a urethral stricture and underwent second surgery with a successful outcome ● At the 6 month follow-up, 14 cats (93%) had only mild urinary signs and 1 had incontinence (6%)
46
Beeston et al JSAP 2023- What clinicopathological findings and point of care ultrasound findings were beneficial for diagnosing cats with ureteral obstruction?
- Point of care ultrasound abnormalities were detected in 81% obstructed cats and 38% non-obstructed cats - Renal pelvis dilation (odds ratio of 38.8), hyporexia (odds ratio 5.9), hypercalcemia (odds ratio 16.6) and hypokalemia (odds ratio 21.7) were more likely to be associated with ureteral obstruction than non-obstructive disease *** Cats with renal pelvis dilation were 39 times more likely to have ureteral obstruction than non-obstructive acute kidney injury