Viral Structure, Function, and Life Cycle Flashcards

(27 cards)

1
Q

Are viruses in the tree of life

A

No

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2
Q

Viral nucleic acid

A

RNA or DNA, single stranded or double stranded, and forward (DNA to RNA) or reverse (RNA to DNA which requires reverse transcriptase)

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3
Q

Viral genes

A

Only have essential genes so structural proteins, replications proteins, and attachment and entry proteins

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4
Q

Naked virus

A

Nucleocapsid - nucleic acid genomes and capsid proteins
Also have virus attachment proteins

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5
Q

Enveloped Virus

A

1nucleic acid genomes, 2capsid proteins, 3envelope with viral attachment proteins

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6
Q

Icosahedral

A

Like a soccer ball, can be enveloped or not

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7
Q

Helical

A

Long tube, always enveloped

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8
Q

Complex

A

Any shape not the other to, can or can not be enveloped

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9
Q

Viral reproduction

A

Requires a host cell, parasitic relationship

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10
Q

Viral life cycle

A

Attachment, entry, uncoating and replication, assembly, release

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11
Q

Two ways of entry

A

Encocytosis (cell brings virus inside through plasma membrane) or direct fusion (viral envelope fuses with host cell and contents are deposited inside)

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12
Q

Two ways or release

A

Lysis and budding

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13
Q

One antiviral medication and its target

A

Fostemasavir blocks viruses from entering a host

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14
Q

Viruses average size

A

.05 um

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15
Q

Antigenic Drift

A

Minor genetic change, mistake during RNA replication

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16
Q

Antigenic shift

A

Major genetic change, 1 host is infected with two viruses -> new strain

17
Q

Enteric Viruses Transmission

18
Q

Respiratory Virus Transmission

A

Respiratory system or saliva

19
Q

Sexually Transmitted Viruses

A

Sexual contact

20
Q

Zoonotic Vires Transmission

A

Animal to human or vectors

21
Q

Acute infections

A

Onset suddenly, short span, host cells usually burst and die, virus disappears after infection

22
Q

Persistent Latent infection

A

Symptoms - none until reactivation, always infected, host cells are unharmed until reactivation, virus stays in host indefinitely but only grows during reactivation

23
Q

Chronic Infection

A

symptoms - mild or absent, continueous low level viral production, host continually releases virus

24
Q

Cancer developement

A

Occurs 15-20 years after infection, host grows into tumor, virus growth stops but viral genome remains

25
Prions
Made of protein, affects neural tissue, causes host neural proteins to misfold and stop working
26
Pathogen
a bacterium, virus, or other microorganism that can cause disease.
27
Influenza life cycle
bind attachment protein (HA) to receptor, enter the cell through endocytosis, uncoating releases nucleic acid, transcription and translation of viral genome, production on viral proteins, assembly of new virions, exit through budding