What are the mechanisms that protect eyes from injury?
Eyeball is sheltered by bony socket in which it is positioned; eyelids (act like shutters to protect eye from environmental hazards); eyelashes (trap fine, airborne debris such as dust before it can fall into eye); tears (continuously produced by lacrimal glands and conjunctiva; lubricate, cleanse, bactericidal)
Sclera
One of three tissue layers (with cornea) that encloses eye; tough outer layer of connective tissue; forms visible white part of the eye
Cornea
One of three tissue layers (with sclera) that encloses eye; anterior, transparent outer layer, allows passage of light rays
Choroid body
One of three tissue layers that encloses eye; middle layer underneath sclera which contains blood vessels that nourish retina; contains dark pigment epithelium (melanin) behind the retina; also forms ciliary body, suspensory ligaments and iris
Retina
Innermost layer under choroid; consists of: outer pigment cells; rods and cones; primary sensory neurons, and axons of visual nerve fibres
Iris
Controls amount of light entering eye; contains two sets of smooth muscle (circular muscle: constrictor; radial muscle: dilator)
Pupil
Opening through which light enters the eye
Lens
Focuses light
Anterior chamber
One of 3 fluid-filled cavities that makes up interior; between cornea and lens; filled with aqueous humor
Posterior chamber
One of 3 fluid-filled cavities that makes up interior; between iris and lens; filled with aqueous humor
Vitreous chamber
One of 3 fluid-filled cavities that makes up interior; behind the lens, largest chamber; filled with vitreous fluid, a gelatinous mass
Tapetum Lucidum
Reflective layer found in many vertebrates (not humans) to replace some of the melanin in the choroid; reflects light back towards retina after its passed the photoreceptors; improves sensitivity of vision under low light, but may cause some blurriness
Dilating/constricting the pupil
Changing pupil size controls the amount of light entering the eye (optimization for light and dark conditions; gives the eye a wide “dynamic range”); also controls depth of field (small aperture gives large depth of field, large aperture reduces depth of field; close objects viewed with constricted pupils, so if object moves short distance it stays in focus)
What controls pupil size?
ANS (parasympathetic -> ACh; sympathetic -> NE)
What has to happen in order to have clear vision?
The focal point must fall on the retina
Accommodation
Process of focusing; change in strength of lens; fast: only takes 350ms to change focus from far to near; accomplished by action of ANS on ciliary muscle (PNS -> ACh; ACh causes contraction of ciliary muscle cells, and constriction of the ring -> leads to increasing lens curvature for close objects; decreasing parasympathetic tone relaxes muscle. causes a flatter lens for distant objects)
*natural shape of lens is strong and rounded; when ciliary muscle is relaxed, it pulls the lens to a flatter, weaker shape
Myopia
Near-sightedness; occurs when the focal point falls in front of the retina
Hyperopia
Far-sightedness; occurs when the focal point falls behind the retina
In what order will light pass through the retina?
Fibres of optic nerve -> ganglion cells -> amacrine cell -> bipolar cell -> horizontal cell -> cone -> rod
Rods
More of them; grayscale vision; high sensitivity (night vision, low acuity); more convergence onto ganglion cells; mainly located in peripheral retina
Cones
Not as many; colour vision (at least 3 varieties); lower sensitivity (high acuity, day vision); less convergence; mainly located in the fovea
Macula
Area of a high concentration of cones; has less convergence of photoreceptors to ganglion cells than peripheral areas; directly opposed to pupil so light strikes there; within macula at the fovea light strikes the receptors directly because overlying neurons are pushed aside (very highest density of cones is at the fovea and there is very little convergence of sensory neurons
Phototransduction
Changing visual information into APs
How does phototransduction occur in darkness?
Rhodopsin is inactive; levels of cGMP are high (cGMP: cyclic nucleotide, intracellular messenger); cyclic nucleotide gated (CNG) Na+/Ca2+ channels and K+ channels are open (cGMP binds to CNG channels and causes them to open); cells are constantly depolarized by entry of Na+ and Ca2+ (tonically release transmitter onto bipolar cells)