Vitamin

Question 1

[Vitamin/Basic]

B1
B2
B3
B5
B6
B7
B9
B12

Answer 1

B1 Thiamine
B2 Riboflavin
B3 Niacin (Nicotinamide)
B5 Pantothenate (coenzyme A)
B6 Pyridoxine
B7 Biotin
B9 Folate
B12 Cobalamin

Question 2

[Vitamin/Basic]

B1

Answer 2

B1 Thiamine

Question 3

[Vitamin/Basic]

B2

Answer 3

B2 Riboflavin

Question 4

[Vitamin/Basic]

B3

Answer 4

B3 Niacin (Nicotinamide)

Question 5

[Vitamin/Basic]

B5

Answer 5

B5 Pantothenate (coenzyme A)

Question 6

[Vitamin/Basic]

B6

Answer 6

B6 Pyridoxine

Question 7

[Vitamin/Basic]

B7

Answer 7

B7 Biotin

Question 8

[Vitamin/Basic]

B9

Answer 8

B9 Folate

Question 9

[Vitamin/Basic]

B12

Answer 9

B12 Cobalamin

Question 10

[Vitamin/B1]

Dietary thiamine deficiency symptoms?

Answer 10

1. BeriBeri (wet: acute heart failure, dry: paresthesia, neuropathies), lactic acidosis
2. Wernicke-Korsakoff: encephalopathy, confabulation, in chronic alcoholism

Question 11

[Vitamin/B1]

Disorders of Thiamine transport (3)?

Answer 11

1. Thiamine-Responsive Megaloblastic Anemia Syndrome
   - anemia, DM, hearing loss, retinitis, cardiomyopathy
2. SLC25A19-Related Thiamine Metabolism Dysfunction
   - acute encephalopathy with illness, flaccid paralysis
3. Biotin+thiamine-responsive basal ganglia disease
   - Leigh-like subacute encephalopathies, dystonia

Question 12

[Vitamin/B1]

Disorders of Thiamine metabolism (1)?

Answer 12

Thiamine PP kinase deficiency
- 7 patients to date
- neurologic symptoms

Question 13

[Vitamin/B2]

Disorders of riboflavin transport (1)?

Answer 13

Brown Vialetto Van Laere syndrome
- defect in riboflavin transporter RFVT2
- bulbar palsy, hearing loss
- biochemical MADD like

Question 14

[Vitamin/B6]

Disorders of pyridoxine metabolism (1)?

Answer 14

Pyridoxine-responsive seizures
- Antiquitin deficiency (Pyridoxine responsive epilepsy)
- PNPO defect