(28) Hypersensitivity IV

Question 1

(Type IV)

1. Does it involve antibodies
2. What happens in it?
3. Do pathological effects take place earlier or later than Type !-III? how much? why?

Answer 1

1. no, not at all
2. T cells directly recognize foreign antigen and cause inflammation and tissure injury
3. later; referred to as delayed (may take up to 24 hours); antigen-specific T cells haveing to increase in numbers

Question 2

(Hypersensitivity IV)

(Contact Hypersensitivity)

1. Highly reactive chemicals that come in contact with the skin can do what?

Answer 2

1. modify self proteins resulting in a CD4 or CD8 T cells response

learn this graph

Question 3

Atopic Dermatitis = type 1 hypersensitivity

Allergic Contact Dermatitis = type IV hypersensitivity

and then look at the delayed type hypersensitivity thing (on this slide)

Question 4

Answer 4

D

Question 5

Answer 5

C

Question 6

Answer 6

B