Types of Lymphocytes
T & B
The big 4 organs of the immune system
• Bone Marrow
• Thymus
• Spleen
• Lymph Nodes
• Formation of white and red blood cells
• Maturation of red cells and many white blood cells
• Site where lymphocytes are first formed
Bone marrow
Lymph nodes increase in size when…
• In response to inflammation
• When infiltrated by tumor
What cavity is the spleen found
Abdomen
What cell types are found in lymph nodes
• T and B Lymphocytes
• Dendritic macrophages
What is the predominant cell type in the
thymus?
T cells
What types of lymphocytes are found in
blood?
• B (most)
• T
• NK
What cell is found in the red pulp?
RBC and monocyte/macrophages
What cells are found in the white pulp?
T and B lymphocytes
Which blood cell type increases in chronic
inflammation?
Monocytes and Lymphocytes
Which cells are part of the adaptive immune response?
T and B lymphocytes
Where do T lymphocytes:
arise?
Mature?
Reside?
Circulate?
Bone marrow
Thymus
Lymph nodes and spleen
Blood and through tissues
a group of cells with identical genetic structure, they all recognize the same antigen
Clone
T cell that kills abnormal cell
Cytotoxic
stimulate the immune response
Helper T cells
tone down the immune response
Suppressor T cells
Where are B lymphocytes found
Mostly lymph nodes and spleen, some in the blood migrating to lymph nodes
Only recognizes one antigen
B lymphocyte
What are the big 4 organs of the immune system
-bone marrow
-thymus
-spleen
-lymph nodes
• Formation of white and red blood cells
• Maturation of red cells and many white blood cells
• Site where lymphocytes are first formed
Bone marrow
migrate from the bone marrow to the
thymus
T lymphocytes
• Starts as tissue fluid (from blood capillaries)
• Added proteins and fats
Lymph
Filters blood
Spleen