AIDs

Question 1

Primary immunodeficiency is:

Answer 1

inherited genetic defect in the immune system
- caused by defects in any gene
- congenital

Question 2

Secondary immunodeficiency is:

Answer 2

loss of immune function due to exposed agent
- HIV/AIDs
- acquired

Question 3

How is AIDs transmitted?

Answer 3

• birth
• heterosexually

Question 4

T/F. AIDs is the deadliest single infectious agent known human pathogen.

Answer 4

True

Question 5

Explain the HIV virion components.

Answer 5

• gp120, gp41
• two RNA genomes
• integrase: cDNA copy is integrated into host cell genome
• reverse transcriptase: uses RNA genome to form cDNA
• protease

Question 6

How is HIV spread?

Answer 6

• unprotected secx
• infected blood
• mother to infant passage

Question 7

What are the first cells to be affected by HIV?

Answer 7

Dendritic cells

Question 8

Which structural genes makes up the three virion enzymes of HIV?
a. gag
b. pol
c. env

Answer 8

b. pol