1
Q
Therapeutic Classification
A
None
2
Q
Pharmacologic Classification
A
Thrombolytic/fibrinolytic
3
Q
Mechanism of Action
A
Converts plasminogen to plasmin, which then dissolves fibrin clots. Also, degrades procoagulant factor V and VIII and lowers circulating amount of fibrinogen and plasminogen.
4
Q
Indications
A
- Thrombotic CVA
- off-label use to restore IV catheter patency.
5
Q
Contraindications
A
- History of CVA in last 3 months
- Recent trauma/surgery
- Active bleeding
- Severe HTN
- Intracranial neoplasm
- AV malformation
6
Q
Drug interactions with anticoagulants, thrombolytic agents, antiplatelet agents, and NSAIDs?
A
Increased risk of bleeding
7
Q
Adverse Effects
A
- *Angioedema
- *intracranial bleeding
- bleeding
- transient dysrhythmias.
8
Q
pregnancy category?
A
Pregnancy Category C
9
Q
Nursing Considerations
A
- Complete health history
- Assess for bleeding
- Avoid invasive procedures
- Keep patient in bed
- Check vital signs frequently
- Apply pressure to puncture sites x 30 minutes
10
Q
Patient & Family Teaching
A
- Remain quiet and on bed rest when receiving this medication
- Report bleeding
Unit II Nursing 160
flashcards
Decks in class (16)
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