What is energy?
The capacity to cause change
kinetic energy
energy in motion
potential energy
stored energy
Conservation of Energy
2. energy can be converted from one form to another
entropy
measure of disorder or randomness in a system
heat
is a type of kinetic energy and product of all energy conversions
chemical energy
* can be released by a chemical reaction.
cellular respiration
• the energy-releasing chemical breakdown of fuel
molecules (ie glucose)
• the storage of that energy in a form the cell can use to
perform work (ie ATP)
energy used by humans
* ~66% as heat
calorie
– A calorie is the amount of energy that can raise
the temperature of one gram of water by 1 ⁰C.
• Food Calories are kilocalories, equal to 1,000 calories.
• The energy of calories in food is burned off by many
activities.
ATP
• acts like an energy shuttle
• stores energy obtained from food
• releases it later as needed
• consists of an organic molecule called adenosine plus a
tail of three phosphate groups and
• is broken down to ADP and a phosphate group, releasing
energy.
phosphate transfer
– ATP energizes other molecules by transferring phosphate groups. – This energy helps cells perform • mechanical work, • transport work, and • chemical work.
ATP cycle
– Cellular work spends ATP continuously.
– ATP is recycled from ADP and a phosphate group
through cellular respiration.
– A working muscle cell spends and recycles up to
10 million ATP molecules per second.
metabolism
total of all chemical reactions in an organism
activation energy
– Activation energy activates the reactants and
• triggers a chemical reaction.
– Enzymes reduce the amount of activation energy
required to break bonds of reactant molecules.
– Enzymes can function over and over again.
– Many enzymes are named for their substrates, but
with an –ase ending
induced fit
– An enzyme is very selective in the reaction it
catalyzes.
– Each enzyme recognizes a substrate, a specific
reactant molecule.
• The active site fits to the substrate, and the enzyme
changes shape slightly.
• This interaction is called induced because the entry of
the substrate induces the enzyme to change shape
slightly
feedback regulation
– Some products of a reaction may inhibit the
enzyme required for its production.
• This is called feedback regulation.
• It prevents the cell from wasting resources.
enzyme inhibitors
• Penicillin blocks the active site of an enzyme that bacteria
use in making cell walls.
• Ibuprofen inhibits an enzyme involved in pain signaling.
• Many cancer drugs inhibit enzymes that promote cell
division.
transport proteins
* help move substances across a cell membrane
passive transports
active transports
• ATPases (ie pumps)
concentration gradient
a region in which the substance’s density
changes.
diffusion
is the movement of molecules so that they spread
out evenly into the available space
osmosis
diffusion of water across a selectively permeable
membrane