Connective tissue proliferates causing nipple to become erect
Neonatal
Hormonally stimulated lobular tissue nay secrete colostrum
Neonatal
1st form of milk produced by the breast
Colostrum
Nipple elevation but no palpable glandular elements
Stage 1, Prepubertal stage
Nipple and breast project as mound from chest wall with palpable tissue in subareolar region
Stage 2, Breast Bud Stage
Increased glandular tissue/ increased areolar size and pigmentation
Stage 3, Breast elevation
Development of separate nipple-areolar complex as secondary mound anterior to breast
Stage 4, Areolar mound/ Visible areolar pigmentation
Final adolescent devt with smooth breast contour
Stage 5, Adult breast
first occurence of menstruation
Menarche
Day 3-14 of menstrual cycle
Proliferative Phase
Follicular Phase of Ovary
Day 15-28 of menstrual cycle
Secretory Phase
Luteal Phase of Ovary
Overall regression of breast epitheliun
Proliferative Phase
Follicular Phase of Ovary
Increase ovarian estrogen production under pituitary control
Proliferative Phase
Follicular Phase of Ovary
Stroma becomes less dense
Proliferative Phase
Follicular Phase of Ovary
Duct lumens expand
Proliferative Phase
Follicular Phase of Ovary
Lowest breast volume and water content
Proliferative Phase
Follicular Phase of Ovary
Stromal density increases
Secretory Phase
Luteal Phase of Ovary
Water content of breast increases
Secretory Phase
Luteal Phase of Ovary
Clinical symptoms relate to
- increased interlobar fluid
-generalized lobular proloferation
Secretory Phase
Luteal Phase of Ovary
Marked ductal and lobular proliferation in early wk of pregnancy
Pregnancy
Generalized breast devt
Wk 5-9 of Pregnancy
Progressive increase in nipple-areolas complex pigmentation
Wk 5-9 of Pregnancy
Progressive lobular proloferation
2nd half of Pregnancy
Stromal and fat elements increase
2nd half of Pregnancy
