E c t o d e r m a l s t r e a k s
d e v e l o p f r o m f e t a l
a x i l l a t o g r o i n
Week 4-6
Mammary ridges develip in thoracuc region
Week 4-6
Milk lines appear (region where breast tissue would potentially develop)
Week 4-6
Mammary ridges involute
Week 6-8
Invagination of chest wall mesenchyme
Week 6-8
Differentiation of smooth muscle of nipple and areola
Week 12-16
Devt of epithelial buds and bud branching
Week 12-16
Devt of hair follicles, apocrine glands, and Montgomery glands
Week 16-20
Appearance of primitive elements of breast parenchyma
Week 16-20
Epidermis depresses into shallow mammary pit
3rd tri
Nipple-areolar complex enlarges and develops pigmentation
3rd tri
Main ducts canalize
3rd tri
Lobules begin differentiation
3rd tri