Cell membrane

Question 1

first account of semi-permeability of cell membrane

• when
• who
• first discovery re composition (2)

Answer 1

• 1890s
• Ernst Overton
• Membrane has lipid nature w Cholesterol and Lecithins

Question 2

behaviour of lipid monolayer

• when
• who
• discovery (2)

Answer 2

• 1917
• Irving Langmuir
• Hydrophilic Heads & Hydrophobic Tails

Question 3

Proposal of Biomolecular Lipid Leaflet Model

• when
• who

Answer 3

• 1925
• Gorter and Grendel

Question 4

Development of Protein-Lipid Sandwich Model

• when
• who
• discovery (1)

Answer 4

• 1935
• Davson and Danielli
• membrane contains PROTEIN SHEETS

Question 5

Proposal of Trilayer Membrane

• when
• who

Answer 5

• 1967
• Robertson

Question 6

Whose (3 inventors) models (2 models) cannot explain how globular proteins can form thin protein sheets and allow substance transport

Answer 6

Davson-Davielli

and
Rovertson

Question 7

What happened in 1966?

• who
• discovery

Answer 7

• Mueller and Rudin
• bilayer with fluidity and self-healing

Question 8

What happened in 1972?

• who
• model

Answer 8

• Singer and Nicolson
• Fluid Mosaic Membrane

Question 9

3 FACTORS that affect fluidity

Answer 9

1. Temperature (direct)
2. Cholesterol (indirect)
3. Fatty Acid (indirect w SF; direct with UF)

Question 10

2 TYPES of fatty acids

Answer 10

1. Saturated
2. Unsaturated

Question 11

Other term for hydrophobic tails

Answer 11

HYDROCARBON TAILS

Question 12

What type of fatty acids a) has a bent tail, b) what do u call that tail c) reason for such

Answer 12

a. unsaturated
b. kink
3. presence of double bonds

Question 13

How many parts in cell membrane

Answer 13

13

Glycoprotein (may carbs na nakadikit sa taas)
Cholesterol is found in between tails

Question 14

3 main components of the cell membrane

Answer 14

1. lipids
2. proteins
3. carbohydrates

Question 15

2 examples of carbohydrates found in cell membrane

Answer 15

glycolipids

glycoproteins

Question 16

2 examples of lipids found in cell membrane

Answer 16

phospholipids

sterol

Question 17

Two main features in FLUID MOSAIC MEMBRANE

Answer 17

fluidity and mosaicity

Question 18

3 types of proteins

Answer 18

Integral Proteins: Act as channels, receptors, or transporters across the membrane.

Peripheral Proteins: Provide support, cell shape, and signaling near the membrane.

Lipid-Anchored Proteins: Involved in cell signaling and can localize to specific membrane regions.

Question 19

How is semi-permeability shown in cell membrane

Answer 19

phospholipid layer

integral proteins

Question 20

MOLECULES THAT

• cannot pass
• can pass

Answer 20

CANNOT: large,polar,charged

CAN: small, nonpolar, uncharged

Question 21

Function of GLYCOCALYX

Answer 21

Antigenic Function

Question 22

Where are carbs attached

Answer 22

proteins and lipids