Cell signalling

Question 1

What is it?

Answer 1

behaviour of cell during development depends on intercellular communication that
co-ordinates growth, differentiation + metabolism, homeostasis

Question 2

Autocrine

Answer 2

inside cell to other part of cell

Question 3

Extracellular

Answer 3

signal (primary messenger) – receptor – secondary messenger

(signaling cascade) – response

Question 4

Intracellular

Answer 4

biochemical reactions within cell, induced cell death, cell

proliferation, differentiation

Question 5

Why cell signaling is important?

Answer 5

• Control cell metabolism
• Cell division, cell growth, cell differentiation
• Cells respond to SPECIFIC signals
• Control of HOMEOSTSIS.

Question 6

Types of signaling molecules

Answer 6

Lipophilic- steroid hormones, thyroid hormones, vitamin D

2. Hydrophilic- Insulin, glucagon, growth receptors, adrenaline, noradrenaline
3. Local mediators - numerous growth factors- CO. NO. histamines