The body is made up of four types of tissues:
connective -
Epithelial - skin
Muscle - muscle
nervous tissue - neurons
The cell theory:
Theodor Schwann (1810–1882)
All cells arise from existing cells
The cell is the basic functional unit of all living things
All organism has one or more cells
Not applied to neurons!!!
Reticular theory:
Camillo Golgi (1843–1946)
Invented a staining method that permitted researchers to clearly observe all the parts of neurons
The idea that the neurites (axons and dendrites) of neurons fuse with the neurites of other neurons in a neural net
Methods to study neurons:
histology
microscopy
microtome
Isotropic fractionation:
A method by which the number of cells in a brain area of interest can be estimated
human brain contains, on average, 86.06 billion neurons and 84.61 billion glia
neuron types
sensory
motor
interneuron
bipolar and unbipolar
multipolar
pyramidal
stellate
rosehip
how do neurons communicate
neurons communicate through electrical impulses called action potentials,
neurotrasmitters
Action potentials result in the release of neurotransmitters onto specialized receptors situated on target cells.
sections of the brain
coronal plane/frontal - front and back section
horizontal plane - top and bottom
sagittal plane/middle - left and right section
brain directions
superior - top of brain
caudal left
rostral - right
inferior - bottom
structure of neuron
cell body - soma -
Dendrites -
axon
terminal buttons
dentrites
receive info from other neurons and synapses and decide what it is
changes in structure is important for learning and neural develop
cell body soma
contains a nucleus and organelles
integrates incoming signals
It has a threshold; if the chemical energy passes it, the soma passes it on to the axon hillock
Protein synthesis is responsible for translating the genetic info stored in the nucleus into proteins
axon hillock
when soma decides this signal is enough for me to pass it on, it passes it to axon hillock and axon
site for generation and initiation of action potential
does the convert the chemical impulses to electrical impulses
axon
some long and some short
long projection of a neuron that conducts electriacal to
action potential - how it is generated
is really the ion movement within a neuron
if the input is strong enough, the neuron becomes less negative,
it needs to reach the activation threshold
then the sodium ion opens, and due to permeablity sodium comes in and the neuron is more positive
the spike that we see on the graph we call ap
depolarization and repolarization
possitive ions rushing in like sodium - neuron fires
repolarization - potassium running out - rest begins
hyperpolarization
undershoot na and k pump restores - ready again
all or nothing principal
the threshold that makes the neuron fire or not fire
myelinated & unmyelinated
the one that has it is fast and efficient signalling,
un is slower with continuous signalling
axon terminal
electrical signalling is changed back to the chemical
in preparation to be passed on to dendrites
presynaptic neuron
post synaptic neuron
pre - the one releasing the neurotransmitter
post- the neuron that receives it,
info crosses the synapse between these neurons, only chemical can be transferred
synapses
site of communication
explain diffusion
process that molecules move from high concentration to low
when a particular have a high concentration, it diffuses to balance it out