sleep
Its reversible
Naturally occurring state of reduced responsiveness to the environment
Accompanied by characteristic brain patterns
thalamus relay sleep
restorative function of sleep
cellular repair - growth
-tissue/muscle repair
-increase growth hormone secretion
energy restoration
-reduced metabolic activity
-core body temp + glucose
waste clearance
immune support
cognitive function of sleep
Memory consolidated
-short mem to long
hippocampal replay + synaptic strengthening
learning integration
-new info integrate with existing
emotional regulation
process emotional
physiological
Hormonal regulation
-balance hormone
appetite/stress vary across different stages
metabolic regulation
cardiovascular recovery
circadian rhythm synchronization
sleep architecture
NREM VS REM
90 min cycle for each sleep
non repeat and repeat eye movement
NREM
N1 -
N2 -
N3 -
REM
N1
light sleep, dozing off in a meeting,
5%
N2
deeper than N1, Theta waves, sleep spindle/K-complex
heart rate slows, no eye movement
50%
N3
deep sleep/slow wave, restorative function
delta waves - slow
high amp
Blood pressure is low
bbb is active
hardest stage to wake someone up from
groggy and disoriented
night terror or sleepwalking happen at this stage
REM sleep
20% of sleep
paradoxical sleep
brain looks awake but body is sleep
combo of alpha and thet,
amygdala is active - emotion
neural control N1
reticular formation
thalamus
cortex
neura control N2
Hippocampus turns short term memory to long
thalamus even more active - stricter that is why it is not easier to wake someone up at this sleep
neural control N3
VLPO - in the hypothalamus
ventrolateral preoptic nucleus
brains deep cleaning and recovery cycle
neural control REM - muscle atonia
pons communicate with thalamus
pons inhibits medula - loss of muscle control called muscle atonia
sleep walking - pons not inhibiting medula properly
amygdala active - waking up happy or not
circadian rhythm
Internal time keeper for waking up and falling sleep
Hypothalamus - sleep/awake switch
VLPO
Thalamus - cortical activation, sleep spindles, EEG
Suprachiasmtic nucleus
circadian clock
melatonin
Brain stem ascending cortical activation
morning/night
Morning light hits the eye,
suprachiasmatic
melatonin is supresses
SEN activated the pineal gland at night
melatonin is activated
evening and morning
process C
go to sleep or awake
process S
the pressure we feel since waking
the more pressure build up the more tired
nocturnal lagophthalmos
not being able to shut the eye when sleep