Chapter 24 - Developmental Embryology Flashcards

12/11/25 (56 cards)

1
Q

What is embryology?

A

The study of development from fertilization to birth.

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2
Q

Why is embryology important?

A

It explains how tissues, organs, and systems form and helps understand congenital defects.

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3
Q

What are the key stages of embryonic development?

A

Fertilization → Cleavage → Blastulation → Gastrulation → Organogenesis → Fetal development.

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4
Q

What is prenatal development?

A

Growth from conception to birth.

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5
Q

What is postnatal development?

A

Growth from birth to adulthood.

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6
Q

What is fertilization?

A

Fusion of sperm and egg to form a zygote.

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7
Q

What chromosome number is restored at fertilization?

A

Diploid (2n), half from sperm and half from egg.

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8
Q

Where does fertilization occur?

A

Ampulla of the fallopian tube.

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9
Q

How long is the egg viable?

A

About 24 hours.

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10
Q

How long can sperm survive?

A

3–5 days.

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11
Q

What is capacitation?

A

Biochemical changes that increase sperm motility and prepare it for fertilization.

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12
Q

What is the acrosomal reaction?

A

Sperm enzymes digest the zona pellucida to enter the egg.

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13
Q

What is the cortical reaction?

A

Hardening of the zona pellucida to prevent polyspermy.

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14
Q

What is nuclear fusion (syngamy)?

A

Fusion of sperm and egg nuclei to form a diploid zygote.

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15
Q

What is cleavage?

A

Rapid mitotic divisions without growth.

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16
Q

What cells are formed during cleavage?

A

Blastomeres.

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17
Q

What is a morula?

A

A solid ball of 16–32 cells.

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18
Q

When does cleavage begin?

A

About 24 hours after fertilization.

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19
Q

What are the stages of cleavage?

A

2-cell → 4-cell → 8-cell → Morula.

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20
Q

What is holoblastic cleavage?

A

Complete division (humans).

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21
Q

What is meroblastic cleavage?

A

Partial division (birds, reptiles, fish).

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22
Q

What is blastulation?

A

Formation of the blastocyst.

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23
Q

When does blastulation occur?

A

Day 4–5 after fertilization.

24
Q

What are the parts of the blastocyst?

A

Trophoblast, inner cell mass, blastocoel.

25
What does the trophoblast become?
Placenta and chorion.
26
What does the inner cell mass form?
The embryo and amnion.
27
When does implantation occur?
Day 6–7 after fertilization.
28
What happens during implantation?
Blastocyst attaches to the endometrium and begins nutrient exchange.
29
What is gastrulation?
Formation of three germ layers and the body plan.
30
What are the three germ layers?
Ectoderm, mesoderm, endoderm.
31
What does ectoderm form?
Skin, nervous system, hair, nails, sensory organs.
32
What does mesoderm form?
Muscles, bones, heart, kidneys, gonads.
33
What does endoderm form?
Digestive tract, lungs, liver, pancreas, bladder, thyroid.
34
What is the notochord?
A mesodermal rod that induces neural development.
35
What is neurulation?
Formation of the neural tube.
36
What does the neural tube become?
Brain and spinal cord.
37
What do neural crest cells form?
Peripheral nervous system and facial structures.
38
When does neurulation occur?
Around week 3.
39
What is organogenesis?
Germ layers forming organs and systems.
40
When does organogenesis begin?
Around week 3.
41
When does the heart begin beating?
Week 4.
42
What is the critical period?
Weeks 3–8 (highest risk for birth defects).
43
When do limb buds appear?
Weeks 4–5.
44
When do lungs and kidneys begin developing?
Weeks 5–6.
45
When do facial features start forming?
Weeks 6–8.
46
What are extraembryonic structures?
Tissues that support the embryo but don’t become the baby.
47
What is the amnion’s function?
Cushions, protects, allows movement, aids lung development.
48
What is the yolk sac’s role?
Early blood cell and vessel formation.
49
What does the chorion form?
Placenta and nutrient exchange structures.
50
What is the allantois?
Forms blood vessels of the umbilical cord and contributes to the bladder.
51
What forms the placenta?
Fetal chorion + maternal endometrium.
52
What does the placenta do?
Exchanges gases, nutrients, wastes, and secretes hormones.
53
When does fetal development occur?
Week 9 to birth.
54
What happens in the first trimester?
Organogenesis completes; high sensitivity to teratogens.
55
What happens in the second trimester?
Rapid growth and fetal movement felt.
56
What happens in the third trimester?
Weight gain, lung maturity, brain growth, passive immunity.