Energy Metabolism
How body obtains & uses energy
from food
Liver cells
most versatile & metabolically active(a lot of reactions and gluconeogenesis
Anabolism (and requires what)
- Requires energy (building reaction)
Catabolism(releases what)
breaking down of body compounds
-Releases -energy (breakdown reaction
Coupled Reactions
– Hydrolysis (breakdown) of ATP occurs at same time as reactions that will USE energy to build compounds
What is ATP used for?
Body uses ATP to transfer the energy released during CATABOLIC reaction to power its anabolic reaction
“Energy” to ATP
50%
Coenzymes
- B vitamins can act as coenzymes
Whats derived from CHo
glucose
Whats derived from PRO
amino acids
Whats derived from TG
glycerol and fatty acids
Discuss pyruvate in general
- can be used to make glucose
Discuss Acetyl CoA
- cannot be used to make glucose
Where are the hydrogen atoms carried?
to the electron transport chain
What is glucose splitting
glycolysis
Can pyruvate be converted back to glucose?
yes
Two Pyruvate Energy Need Options
- aerobic
Anaerobic
Aerobic
slower energy needs
-pyruvate to acetyl COa
Pyruvate to Lactate Effects
-hydrogen(which causes burning)
Cori Cycle
lactate taken to liver and reconverted into glucose
Where does pyruvate enter and what’s removed?
- carbon removed ……becomes carbon dioxide
What makes acetyl Coa and is it undoable?
- irreversible
Acetyl Coa’ options
2. generate ATp through TCA cycle