Chapter 7: Harmful Effects

Question 0

Overdose of BZDs (2)

Answer 0

1. not usually lethal and is easily treated with flumazenil

2. fatalities usaully involve concurrent use of alcohol

Question 1

Reproduction
withdrawal infants?
Floppy baby syndrome?
-drugs presence in baby after brith?

Answer 1

• generally not a problem except for infants of mothers who took BDZs chronically while prego …behavioural teratogenic effects (rats), absence of locomotion responses and the acoustic startle responses
• withdrawal symptoms in infants…tremors, irritability, and hyperactivity
• depressing respiration, reluctance to feed and decreasing the ability to maintain norm body temp.
• up to 8 days after delivery (drugs presence)

Question 2

BARBs

Answer 2

have high overdose risk ….whereas BZDs do not

Question 3

Deaths solely due to BZDs would be ?

Answer 3

due to shorter acting drugs like nitrazepam, temazepam and flunitrazepam…

Question 4

Doses as high as 2,250 mg of BZDs can be tolerated with :

Answer 4

• no deep coma or severe respiratory depression and victims can usually be awakened
• sleep and drowsiness