Functions of skeletal muscle
Tissues in Skeletal muscle
Myofibrils
Actin and myosin are arranged in long fibers.
- these do the contraction, and there are lots of them in each muscle fiber
T Tubules
Sarcoplasmic reticulum
stores lots of calcium ions, which when released start a contraction
Fascicles
-Bundles of skeletal Muscle fibers surrounded or enclosed with endomysium connective tissue.
Endomysium
perimysium
Gaps around various fascicles are filled with perimysium
- divides muscles into compartments between the fascicles
Epimysium
Collagen sheath/ barrier or membrane of the muscle
Relation between endomysium, perimysium, and epimysium is. . .
The collagen fibers of all 3 connective tissue layers connect at the ends of the muscle to form one of tow structures:
Tendon
Bundle of collagen (dense Regular connective tissue) hooking muscle to bone
Aponeurosis
Broad sheet of collagen fibers connecting a muscle to the next muscle
sarcomere
Dark, Thick filaments are made of
Myosin
Light, Thin filaments are made of
actin
H band
is the part of the A band that has myosin but not actin in it
M line
strands of protein arranged perpendicular to the rest of the sarcomere to keep all of the myosin aligned
Z line
The boundary between sarcomeres is made of interconnecting proteins
Steps of a muscle contraction
Step 0: Neurotransmitter Ach released
Step 1: Ach binds to muscle
Step 2: Ach changes membrane polarity start an action potential
Step 3: Action potential gets moved down the t tubules until it gets to the sarcoplasmic reticulum (stores calcium)
Step 4: calcium ion gets released into the cytoplasm
Step 5: Calcium binds to troponin which tells tropomyosin to move off of the actin
Step 6:Myosin head binds to actin (cross bridging)
Step 7: Myosin head releases ADP and phosphate to swivel its head around
Step 8: Contraction of myosin head
Step 9: Need Another ATP to release from actin and relax muscle
Step 10: Myosin breaks down new ATP into ADP and phosphate to release from actin and swivel back to it’s starting position
Step 11: resetting or builds towards tetanus
Contraction: latent period
the time it takes for the action potential to result in calcium release from the sarcoplasmic reticulum
Contraction: Contraction phase
Tension from the contraction of the muscle fibers peaks as myosin binds to actin and pivots
Contraction: Relaxation phase
the cell resets. Calcium is pumped back into the sarcoplasmic reticulum, myosin releases, and active sites are covered back up with tropomyosin.
Tetanus (physiologic)
Maximum amount of muscle tension
Tetanus (the disease)