what are the two major phenotypes of COPD?
chronic bronchitis and emphysema
what is chronic bronchitis?
it is characterized by airway inflammation and obstruction of the smaller airways
when is chronic bronchitis diagnosed?
a history of chronic productive cough for at least 3 consecutive months over 2 consecutive years is required for clinical diagnosis
what is emphysema?
is characterized by loss of lung elasticity and abnormal enlargement of the air spaces distal to the terminal bronchioles with destruction of the alveolar walls and capillary beds