how is COPD defined?
as a respiratory disorder (group of disorders) largely caused by smoking, characterized by progressive, partially reversible airway obstruction and lung hyperinflation systemic manifestations, and increasing frequency and severity of exacerbations
what is COPD characterized by?
by persistent inflammation of airways, lung parenchyma and its vasculature
what is the pathophysiological hallmark of COPD?
is expiratory flow limitation