Crohn's Mx

Question 1

inducing remission

Answer 1

1. glucocorticoids
2. 5 ASA drugs (e.g. mesalazine) 2nd line option
3. azathioprine or mercaptopurine may be used as add on therapy to induce remission

Question 2

inducing remission - refractory disease + fistulating Crohns

Answer 2

infliximab

Question 3

inducing remission - isolated peri-anal disease

Answer 3

metronidazole

Question 4

maintaining remission

Answer 4

1. azathioprine or mercaptopurine

2. 2nd line is methotrexate

Question 5

what should be assessed before starting azathioprine or mercaptopurine

Answer 5

TPMT activity