UC Mx

Question 1

severity - mild

Answer 1

< 4 stools/day

only small amount of blood

Question 2

severity - moderate

Answer 2

4-6 stools per day
varying amount of blood
no systemic upset

Question 3

severity - severe

Answer 3

> 6 bloody stools per day

features of systemic upset

Question 4

inducing remission - mild/moderate: proctitis

Answer 4

1. topical (rectal) aminosalicylate
2. if no remission 4wks add oral aminosalicylate
3. then add oral corticosteroid

Question 5

inducing remission - mild/moderate: proctosigmoiditis + L sided UC

Answer 5

1. topical (rectal) aminosalicylate
2. add high dose oral aminosalicylate or switch to high dose oral amisosalicylate + topical corticisteroid
3. oral aminosalicylate and oral corticosteroid

Question 6

inducing remission - mild/moderate: extensive disease

Answer 6

1. topical aminisalicylate + high dose oral aminosalicylate

2. high dose oral aminosalicylate and oral corticosteroid

Question 7

inducing remission - severe colitis

Answer 7

hospital treatment
IV steroids

if no improvement 72hrs consider adding IV ciclosporin to IV steroids

Question 8

Maintaining remission: proctitis + proctosigmoiditis

Answer 8

topical aminosalicylate
or
oral aminosalicylate + topical aminosalicylate
or
oral aminosalicylate

Question 9

Maintaining remission - L sided and extensive UC

Answer 9

low maintenance dose of oral aminosalicylate

Question 10

maintaining remission after severe relapse or ≥2 exacerbations in past year

Answer 10

oral azathioprine or oral mercaptopurine