cytoskeleton 2

Question 1

beta actin

Answer 1

stay on the forefront of a moving cell facilitating motility

Question 2

the actualy act of splitting a cell in half (cytokenesis) is facilitated by…

Answer 2

actin

Question 3

platelet aggregation is facilitated by

Answer 3

actin

Question 4

phagocytosis is mediated by

Answer 4

actin, thereby acting in leprosy, leishmans, and taxoplasmosis

Question 5

microvili

Answer 5

specialized actin structure

-found in intestinal epithelium and function in creating more surface area for nutrient absorption

Question 6

RBC with regards to intermediate filaments

Answer 6

• they have specialized actin known as spectrin
• great model for cell structure because they have to so strong in order to survive high pressure and squeezing through spleen
• defetcs in actin lead to hereditary spherocytosis

Question 7

hereditary spherocytosis

Answer 7

• this is caused by a mutation that creates dysfunctional actin in RBCs
• the cells get caught up in the spleen and consumed by macrophages
• causes splenomegaly and anemia

Question 8

intermediate filament basic shape

Answer 8

looks like a twisted rope, this confers strength to the strand

Question 9

Intermediate filament found in these cell types:

• nucleated cells
• mesenchymal cells including endothelial cells and fibroblasts
• muscle
• glial cells
• neurons
• epithelial cells

Answer 9

• nucleated cells: lamins
• mesenchymal: vimentin
• muscle: desmin
• glial: glial fibrilary acidic protein (GFAP)
• neurons: neurofilament
• epithelial cells: keratin

Question 10

desmosome and hemidesmosomes

Answer 10

these are cell adhesion molcules which are composed of intermediate filaments.
-prominent in skin cells
(if there is a defect, it causes blistering disease)
-connect cells to each other and to the basement membrane